|
Name |
Accession |
Description |
Interval |
E-value |
| Map |
COG0024 |
Methionine aminopeptidase [Translation, ribosomal structure and biogenesis]; |
88-323 |
2.77e-106 |
|
Methionine aminopeptidase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 439795 [Multi-domain] Cd Length: 250 Bit Score: 310.40 E-value: 2.77e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 88 GVRMACRVAADILKRAGhRIVKPGITTAQVDKAIHEMIIEHGAYPSPLGYSNYPKSCTTSINNVIVHGIPDNRPLHPQDI 167
Cdd:COG0024 11 KMREAGRIVAEVLDELA-EAVKPGVTTLELDRIAEEFIRDHGAIPAFLGYYGFPKSICTSVNEVVVHGIPSDRVLKDGDI 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 168 INIDLTIYLDGYHGDTSATFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHGFSVNSQISGHGI 247
Cdd:COG0024 90 VNIDVGAILDGYHGDSARTFVVGEVSPEARRLVEVTEEALYAGIAAAKPGNRLGDIGHAIQSYAESNGYSVVREFVGHGI 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 50260954 248 GKVFHQPPWIFHDVNSEPG-KMMPGDCFTIEPCLVQGvNSRGDIWDDGWTLATRTGARAAQFEHQVLITDDGVEILS 323
Cdd:COG0024 170 GREMHEEPQVPNYGRPGRGpRLKPGMVLAIEPMINAG-TPEVKVLDDGWTVVTKDGSLSAQFEHTVAVTEDGPEILT 245
|
|
| MetAP1 |
cd01086 |
Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and ... |
88-323 |
9.07e-106 |
|
Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
Pssm-ID: 238519 [Multi-domain] Cd Length: 238 Bit Score: 308.65 E-value: 9.07e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 88 GVRMACRVAADILKRAGhRIVKPGITTAQVDKAIHEMIIEHGAYPSPLGYSNYPKSCTTSINNVIVHGIPDNRPLHPQDI 167
Cdd:cd01086 3 GMREAGRIVAEVLDELA-KAIKPGVTTKELDQIAHEFIEEHGAYPAPLGYYGFPKSICTSVNEVVCHGIPDDRVLKDGDI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 168 INIDLTIYLDGYHGDTSATFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHGFSVNSQISGHGI 247
Cdd:cd01086 82 VNIDVGVELDGYHGDSARTFIVGEVSEEAKKLVEVTEEALYKGIEAVKPGNRIGDIGHAIEKYAEKNGYSVVREFGGHGI 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 50260954 248 GKVFHQPPWIFHD-VNSEPGKMMPGDCFTIEPCLVQGvNSRGDIWDDGWTLATRTGARAAQFEHQVLITDDGVEILS 323
Cdd:cd01086 162 GRKFHEEPQIPNYgRPGTGPKLKPGMVFTIEPMINLG-TYEVVTLPDGWTVVTKDGSLSAQFEHTVLITEDGPEILT 237
|
|
| PRK05716 |
PRK05716 |
methionine aminopeptidase; Validated |
79-324 |
6.52e-98 |
|
methionine aminopeptidase; Validated
Pssm-ID: 235576 [Multi-domain] Cd Length: 252 Bit Score: 289.34 E-value: 6.52e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 79 IALGSKEEW-GVRMACRVAADILKRAGhRIVKPGITTAQVDKAIHEMIIEHGAYPSPLGYSNYPKSCTTSINNVIVHGIP 157
Cdd:PRK05716 3 ITIKTPEEIeKMRVAGRLAAEVLDEIE-PHVKPGVTTKELDRIAEEYIRDQGAIPAPLGYHGFPKSICTSVNEVVCHGIP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 158 DNRPLHPQDIINIDLTIYLDGYHGDTSATFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHGFS 237
Cdd:PRK05716 82 SDKVLKEGDIVNIDVTVIKDGYHGDTSRTFGVGEISPEDKRLCEVTKEALYLGIAAVKPGARLGDIGHAIQKYAEAEGFS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 238 VNSQISGHGIGKVFHQPPWIFHDVNSEPG-KMMPGDCFTIEPCLVQGvNSRGDIWDDGWTLATRTGARAAQFEHQVLITD 316
Cdd:PRK05716 162 VVREYCGHGIGRKFHEEPQIPHYGAPGDGpVLKEGMVFTIEPMINAG-KREVKTLKDGWTVVTKDGSLSAQYEHTVAVTE 240
|
....*...
gi 50260954 317 DGVEILSI 324
Cdd:PRK05716 241 DGPEILTL 248
|
|
| PLN03158 |
PLN03158 |
methionine aminopeptidase; Provisional |
41-323 |
3.36e-88 |
|
methionine aminopeptidase; Provisional
Pssm-ID: 215607 [Multi-domain] Cd Length: 396 Bit Score: 269.78 E-value: 3.36e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 41 VPDHIRRPQyvpinfftapWGEHNIPEMGVDNETEGARIALGSKEEWGVRMACRVAADILKRAGhRIVKPGITTAQVDKA 120
Cdd:PLN03158 108 VPDHIPKPD----------WALDGTPKIEPNSDLQHSVEIKTPEQIQRMRETCRIAREVLDAAA-RAIKPGVTTDEIDRV 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 121 IHEMIIEHGAYPSPLGYSNYPKSCTTSINNVIVHGIPDNRPLHPQDIINIDLTIYLDGYHGDTSATFVLPEVDKLGRELV 200
Cdd:PLN03158 177 VHEATIAAGGYPSPLNYHFFPKSCCTSVNEVICHGIPDARKLEDGDIVNVDVTVYYKGCHGDLNETFFVGNVDEASRQLV 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 201 SATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHGFSVNSQISGHGIGKVFHQPPWIFHDV-NSEPGKMMPGDCFTIEPC 279
Cdd:PLN03158 257 KCTYECLEKAIAIVKPGVRYREVGEVINRHATMSGLSVVKSYCGHGIGELFHCAPNIPHYArNKAVGVMKAGQVFTIEPM 336
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 50260954 280 LVQGVnSRGDIWDDGWTLATRTGARAAQFEHQVLITDDGVEILS 323
Cdd:PLN03158 337 INAGV-WRDRMWPDGWTAVTADGKRSAQFEHTLLVTETGVEVLT 379
|
|
| PRK12896 |
PRK12896 |
methionine aminopeptidase; Reviewed |
75-322 |
6.45e-86 |
|
methionine aminopeptidase; Reviewed
Pssm-ID: 237252 [Multi-domain] Cd Length: 255 Bit Score: 259.00 E-value: 6.45e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 75 EGARIALGSKEEW-GVRMACRVAADILKRAGhRIVKPGITTAQVDKAIHEMIIEHGAYPSPLGYSNYPKSCTTSINNVIV 153
Cdd:PRK12896 4 EGRGMEIKSPRELeKMRKIGRIVATALKEMG-KAVEPGMTTKELDRIAEKRLEEHGAIPSPEGYYGFPGSTCISVNEEVA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 154 HGIPDNRPLHPQDIINIDLTIYLDGYHGDTSATFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKR 233
Cdd:PRK12896 83 HGIPGPRVIKDGDLVNIDVSAYLDGYHGDTGITFAVGPVSEEAEKLCRVAEEALWAGIKQVKAGRPLNDIGRAIEDFAKK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 234 HGFSVNSQISGHGIGKVFHQPPWIFH--DVNSEPGKMMPGDCFTIEPCLVQGVNSrGDIWDDGWTLATRTGARAAQFEHQ 311
Cdd:PRK12896 163 NGYSVVRDLTGHGVGRSLHEEPSVILtyTDPLPNRLLRPGMTLAVEPFLNLGAKD-AETLDDGWTVVTPDKSLSAQFEHT 241
|
250
....*....|.
gi 50260954 312 VLITDDGVEIL 322
Cdd:PRK12896 242 VVVTRDGPEIL 252
|
|
| met_pdase_I |
TIGR00500 |
methionine aminopeptidase, type I; Methionine aminopeptidase is a cobalt-binding enzyme. ... |
79-323 |
1.26e-77 |
|
methionine aminopeptidase, type I; Methionine aminopeptidase is a cobalt-binding enzyme. Bacterial and organellar examples (type I) differ from eukaroytic and archaeal (type II) examples in lacking a region of approximately 60 amino acids between the 4th and 5th cobalt-binding ligands. This model describes type I. The role of this protein in general is to produce the mature form of cytosolic proteins by removing the N-terminal methionine. [Protein fate, Protein modification and repair]
Pssm-ID: 129591 [Multi-domain] Cd Length: 247 Bit Score: 237.63 E-value: 1.26e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 79 IALGSKEEW-GVRMACRVAADILKRAgHRIVKPGITTAQVDKAIHEMIIEHGAYPSPLGYSNYPKSCTTSINNVIVHGIP 157
Cdd:TIGR00500 1 ISLKSPDEIeKIRKAGRLAAEVLEEL-EREVKPGVSTKELDRIAKDFIEKHGAKPAFLGYYGFPGSVCISVNEVVIHGIP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 158 DNRPLHPQDIINIDLTIYLDGYHGDTSATFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHGFS 237
Cdd:TIGR00500 80 DKKVLKDGDIVNIDVGVIYDGYHGDTAKTFLVGKISPEAEKLLECTEESLYKAIEEAKPGNRIGEIGAAIQKYAEAKGFS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 238 VNSQISGHGIGKVFHQPPWIFH-DVNSEPGKMMPGDCFTIEPCLVQGvNSRGDIWDDGWTLATRTGARAAQFEHQVLITD 316
Cdd:TIGR00500 160 VVREYCGHGIGRKFHEEPQIPNyGKKFTNVRLKEGMVFTIEPMVNTG-TEEITTAADGWTVKTKDGSLSAQFEHTIVITD 238
|
....*..
gi 50260954 317 DGVEILS 323
Cdd:TIGR00500 239 NGPEILT 245
|
|
| PRK12318 |
PRK12318 |
methionyl aminopeptidase; |
88-324 |
2.02e-61 |
|
methionyl aminopeptidase;
Pssm-ID: 183434 [Multi-domain] Cd Length: 291 Bit Score: 197.35 E-value: 2.02e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 88 GVRMACRVAADILKrAGHRIVKPGITTAQVDKAIHEMIIEHGAYPSPLGYSN--YPKSCTTSINNVIVHGIPDNRPLHPQ 165
Cdd:PRK12318 51 KIRKACQVTARILD-ALCEAAKEGVTTNELDELSRELHKEYNAIPAPLNYGSppFPKTICTSLNEVICHGIPNDIPLKNG 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 166 DIINIDLTIYLDGYHGDTSATFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHGFSVNSQISGH 245
Cdd:PRK12318 130 DIMNIDVSCIVDGYYGDCSRMVMIGEVSEIKKKVCQASLECLNAAIAILKPGIPLYEIGEVIENCADKYGFSVVDQFVGH 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 246 GIGKVFHQPPWIFHDVNSEPGKMMPGDCFTIEPCLvqGVNSRGDIWD--DGWTLATRTGARAAQFEHQVLITDDGVEILS 323
Cdd:PRK12318 210 GVGIKFHENPYVPHHRNSSKIPLAPGMIFTIEPMI--NVGKKEGVIDpiNHWEARTCDNQPSAQWEHTILITETGYEILT 287
|
.
gi 50260954 324 I 324
Cdd:PRK12318 288 L 288
|
|
| Peptidase_M24 |
pfam00557 |
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ... |
92-316 |
7.96e-46 |
|
Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Pssm-ID: 459852 [Multi-domain] Cd Length: 208 Bit Score: 154.32 E-value: 7.96e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 92 ACRVAADILKRAGHRIvKPGITTAQVDKAIH-EMIIEHGAypsplGYSNYPKSCTTSINNVIVHGIPDNRPLHPQDIINI 170
Cdd:pfam00557 6 AARIAAAALEAALAAI-RPGVTERELAAELEaARLRRGGA-----RGPAFPPIVASGPNAAIPHYIPNDRVLKPGDLVLI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 171 DLTI-YLDGYHGDTSATFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHGFSVNS-QISGHGIG 248
Cdd:pfam00557 80 DVGAeYDGGYCSDITRTFVVGKPSPEQRELYEAVLEAQEAAIAAVKPGVTGGDVDAAAREVLEEAGLGEYFpHGLGHGIG 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 50260954 249 KVFHQPPWIFHdvNSEPGKMMPGDCFTIEPclvqgvnsrGDIWDDGWtlatrtgaRAAQFEHQVLITD 316
Cdd:pfam00557 160 LEVHEGPYISR--GGDDRVLEPGMVFTIEP---------GIYFIPGW--------GGVRIEDTVLVTE 208
|
|
| PRK12897 |
PRK12897 |
type I methionyl aminopeptidase; |
106-323 |
9.84e-41 |
|
type I methionyl aminopeptidase;
Pssm-ID: 171806 Cd Length: 248 Bit Score: 142.48 E-value: 9.84e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 106 RIVKPGITTAQVDKAIHEMIIEHGAYPSPLGYSNYPKSCTTSINNVIVHGIPDNRPLHPQDIINIDLTIYLDGYHGDTSA 185
Cdd:PRK12897 29 KIMKPGITTKEINTFVEAYLEKHGATSEQKGYNGYPYAICASVNDEMCHAFPADVPLTEGDIVTIDMVVNLNGGLSDSAW 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 186 TFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHGFSVNSQISGHGIGKVFHQPPWIFHDVNSEP 265
Cdd:PRK12897 109 TYRVGKVSDEAEKLLLVAENALYKGIDQAVIGNRVGDIGYAIESYVANEGFSVARDFTGHGIGKEIHEEPAIFHFGKQGQ 188
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 266 G-KMMPGDCFTIEPCLVQGVN-SRGDIwdDGWTLATRTGARAAQFEHQVLITDDGVEILS 323
Cdd:PRK12897 189 GpELQEGMVITIEPIVNVGMRySKVDL--NGWTARTMDGKLSAQYEHTIAITKDGPIILT 246
|
|
| APP_MetAP |
cd01066 |
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as ... |
89-318 |
2.86e-32 |
|
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity compared to other metallo-aminopeptidases, suggesting they play roles in regulation of biological processes rather than general protein degradation.
Pssm-ID: 238514 [Multi-domain] Cd Length: 207 Bit Score: 119.10 E-value: 2.86e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 89 VRMACRVAADILKRAGHRIvKPGITTAQVDKAIHEMIIEHGAYPSPLGYsnypksCTTSINNVIVHGIPDNRPLHPQDII 168
Cdd:cd01066 4 LRKAAEIAEAAMAAAAEAI-RPGVTEAEVAAAIEQALRAAGGYPAGPTI------VGSGARTALPHYRPDDRRLQEGDLV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 169 NIDLTIYLDGYHGDTSATFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHGFSVNSQ-ISGHGI 247
Cdd:cd01066 77 LVDLGGVYDGYHADLTRTFVIGEPSDEQRELYEAVREAQEAALAALRPGVTAEEVDAAAREVLEEHGLGPNFGhRTGHGI 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 50260954 248 GKVFHQPPWIFHDvnsEPGKMMPGDCFTIEPclvqgvnsrgdiwddGWTLATRTGARaaqFEHQVLITDDG 318
Cdd:cd01066 157 GLEIHEPPVLKAG---DDTVLEPGMVFAVEP---------------GLYLPGGGGVR---IEDTVLVTEDG 206
|
|
| PepP |
COG0006 |
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; |
83-323 |
1.52e-28 |
|
Xaa-Pro aminopeptidase [Amino acid transport and metabolism];
Pssm-ID: 439777 [Multi-domain] Cd Length: 299 Bit Score: 111.84 E-value: 1.52e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 83 SKEEW-GVRMACRVAADILKRAgHRIVKPGITTAQVDKAIHEMIIEHGAYpsplgYSNYPKSCTTSINNVIVHGIPDNRP 161
Cdd:COG0006 75 SPEEIeLMRKAARIADAAHEAA-LAALRPGVTEREVAAELEAAMRRRGAE-----GPSFDTIVASGENAAIPHYTPTDRP 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 162 LHPQDIINIDLTIYLDGYHGDTSATFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHGFS---V 238
Cdd:COG0006 149 LKPGDLVLIDAGAEYDGYTSDITRTVAVGEPSDEQREIYEAVLEAQEAAIAALKPGVTGGEVDAAARDVLAEAGYGeyfP 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 239 NSQisGHGIGKVFHQPPWIFHDvnsEPGKMMPGDCFTIEPclvqGvnsrgdIWDDGWtlatrTGARAaqfEHQVLITDDG 318
Cdd:COG0006 229 HGT--GHGVGLDVHEGPQISPG---NDRPLEPGMVFTIEP----G------IYIPGI-----GGVRI---EDTVLVTEDG 285
|
....*
gi 50260954 319 VEILS 323
Cdd:COG0006 286 AEVLT 290
|
|
| MetAP2 |
cd01088 |
Methionine Aminopeptidase 2. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and ... |
94-296 |
2.25e-26 |
|
Methionine Aminopeptidase 2. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
Pssm-ID: 238521 [Multi-domain] Cd Length: 291 Bit Score: 105.80 E-value: 2.25e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 94 RVAADILKRA---GHRIVKPGITTAQVDKAIHEMIIEHGAYPSplgysnYPksCTTSINNVIVHGIP---DNRPLHPQDI 167
Cdd:cd01088 5 REAGEIHRQVrkyAQSLIKPGMTLLEIAEFVENRIRELGAGPA------FP--VNLSINECAAHYTPnagDDTVLKEGDV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 168 INIDLTIYLDGYHGDTSATFvlpEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHGFSVNSQISGHGI 247
Cdd:cd01088 77 VKLDFGAHVDGYIADSAFTV---DFDPKYDDLLEAAKEALNAAIKEAGPDVRLGEIGEAIEEVIESYGFKPIRNLTGHSI 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 50260954 248 GkvfhqpPWIFHDVNSEP-------GKMMPGDCFTIEPClvqGVNSRGDIWDDGWT 296
Cdd:cd01088 154 E------RYRLHAGKSIPnvkggegTRLEEGDVYAIEPF---ATTGKGYVHDGPEC 200
|
|
| PRK07281 |
PRK07281 |
methionyl aminopeptidase; |
107-323 |
6.20e-22 |
|
methionyl aminopeptidase;
Pssm-ID: 180918 Cd Length: 286 Bit Score: 93.37 E-value: 6.20e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 107 IVKPGITTAQVDKAIHEMIIEHGAYPSPLG----YSNYPKSCTTSINNVIVHGIPDNRPLHPQDIINIDLTI-------- 174
Cdd:PRK07281 30 LIKPGVDMWEVEEYVRRRCKEENVLPLQIGvdgaMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLsepldksi 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 175 ----------------YLDGYHG---DTSATFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHG 235
Cdd:PRK07281 110 vdvsklnfdnveqmkkYTESYRGglaDSCWAYAVGTPSDEVKNLMDVTKEAMYRGIEQAVVGNRIGDIGAAIQEYAESRG 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 236 FSVNSQISGHGIGKVFHQPPWIFHDVNSEPG-KMMPGDCFTIEPCLVQGVNSRGDIWDDGWTLATRTGARAAQFEHQVLI 314
Cdd:PRK07281 190 YGVVRDLVGHGVGPTMHEEPMVPNYGTAGRGlRLREGMVLTIEPMINTGTWEIDTDMKTGWAHKTLDGGLSCQYEHQFVI 269
|
....*....
gi 50260954 315 TDDGVEILS 323
Cdd:PRK07281 270 TKDGPVILT 278
|
|
| APP-like |
cd01092 |
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse ... |
88-278 |
1.29e-21 |
|
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline.
Pssm-ID: 238525 [Multi-domain] Cd Length: 208 Bit Score: 90.65 E-value: 1.29e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 88 GVRMACRVAADILKraghrIVKPGITTAQVDKAIHEMIIEHGAYpsplGYSnYPKSCTTSINNVIVHGIPDNRPLHPQDI 167
Cdd:cd01092 7 AARIADKAFEELLE-----FIKPGMTEREVAAELEYFMRKLGAE----GPS-FDTIVASGPNSALPHGVPSDRKIEEGDL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 168 INIDLTIYLDGYHGDTSATFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHGFS---VNSqiSG 244
Cdd:cd01092 77 VLIDFGAIYDGYCSDITRTVAVGEPSDELKEIYEIVLEAQQAAIKAVKPGVTAKEVDKAARDVIEEAGYGeyfIHR--TG 154
|
170 180 190
....*....|....*....|....*....|....
gi 50260954 245 HGIGKVFHQPPWIfhdVNSEPGKMMPGDCFTIEP 278
Cdd:cd01092 155 HGVGLEVHEAPYI---SPGSDDVLEEGMVFTIEP 185
|
|
| PTZ00053 |
PTZ00053 |
methionine aminopeptidase 2; Provisional |
94-294 |
1.06e-12 |
|
methionine aminopeptidase 2; Provisional
Pssm-ID: 240246 [Multi-domain] Cd Length: 470 Bit Score: 68.20 E-value: 1.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 94 RVAADILK---RAGHRIVKPGIT----TAQVDKAIHEMIIEHGAYPsplGYSnYPKSCttSINNVIVHGIP---DNRPLH 163
Cdd:PTZ00053 162 RRAAEVHRqvrRYAQSVIKPGVKlidiCERIESKSRELIEADGLKC---GWA-FPTGC--SLNHCAAHYTPntgDKTVLT 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 164 PQDIINIDLTIYLDGYHGDTSATFVL-PEVDKLgrelVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHGFSVNSQI 242
Cdd:PTZ00053 236 YDDVCKLDFGTHVNGRIIDCAFTVAFnPKYDPL----LQATKDATNTGIKEAGIDVRLSDIGAAIQEVIESYEVEIKGKT 311
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 50260954 243 ---------SGHGIGkvfhqpPWIFHDVNSEP-------GKMMPGDCFTIEpclVQGVNSRGDIWDDG 294
Cdd:PTZ00053 312 ypiksirnlNGHSIG------PYIIHGGKSVPivkggenTRMEEGELFAIE---TFASTGRGYVNEDL 370
|
|
| Prolidase |
cd01087 |
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline ... |
90-323 |
8.11e-10 |
|
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.
Pssm-ID: 238520 [Multi-domain] Cd Length: 243 Bit Score: 58.35 E-value: 8.11e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 90 RMACRVAADILKRAgHRIVKPGITTAQVDKAIHEMIIEHGAYPSplgysnYPKSCTTSINNVIVHGIPDNRPLHPQDIIN 169
Cdd:cd01087 5 RKACDISAEAHRAA-MKASRPGMSEYELEAEFEYEFRSRGARLA------YSYIVAAGSNAAILHYVHNDQPLKDGDLVL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 170 IDLTIYLDGYHGDTSATF-VLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEI----GKVIGEFSKRHGF---SVNSQ 241
Cdd:cd01087 78 IDAGAEYGGYASDITRTFpVNGKFTDEQRELYEAVLAAQKAAIAACKPGVSYEDIhllaHRVLAEGLKELGIlkgDVDEI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 242 ISG--------HGIGkvfHqppWI---FHDV------NSEPGKMMPGDCFTIEPclvqGV-NSRGDIWDDgwtlatrtga 303
Cdd:cd01087 158 VESgayakffpHGLG---H---YLgldVHDVggylryLRRARPLEPGMVITIEP----GIyFIPDLLDVP---------- 217
|
250 260
....*....|....*....|....*
gi 50260954 304 RAAQF-----EHQVLITDDGVEILS 323
Cdd:cd01087 218 EYFRGggiriEDDVLVTEDGPENLT 242
|
|
| PA2G4-like |
cd01089 |
Related to aminopepdidase M, this family contains proliferation-associated protein 2G4. Family ... |
94-323 |
1.57e-07 |
|
Related to aminopepdidase M, this family contains proliferation-associated protein 2G4. Family members have been implicated in cell cycle control.
Pssm-ID: 238522 Cd Length: 228 Bit Score: 51.18 E-value: 1.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 94 RVAADILKRAGHRIV---KPGITTAQV----DKAIHEMI---------IEHG-AYPSplgysnypkscTTSINNVIVHGI 156
Cdd:cd01089 5 KTAGQIANKVLKQVIslcVPGAKVVDLcekgDKLILEELgkvykkekkLEKGiAFPT-----------CISVNNCVCHFS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 157 P----DNRPLHPQDIINIDLTIYLDGYHGDTSATFVLPEVD---KLGR--ELVSATQEALDLGIRVCKPGVQISEIGKVI 227
Cdd:cd01089 74 PlksdATYTLKDGDVVKIDLGCHIDGYIAVVAHTIVVGAEAetpVTGKkaDVIAAAHYALEAALRLLRPGNQNSDITEAI 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 228 GEFSKRHGF-SVNSQISghgigkvfHQPPWifhDVNSEPGKMMPGDCftiepclvqgvnSRGDIWDDGWTLATRTGARAA 306
Cdd:cd01089 154 QKVIVDYGCtPVEGVLS--------HQLKR---VVSSGEGKAKLVEC------------VKHGLLFPYPVLYEKEGEVVA 210
|
250
....*....|....*..
gi 50260954 307 QFEHQVLITDDGVEILS 323
Cdd:cd01089 211 QFKLTVLLTPNGVTVLT 227
|
|
| PRK14576 |
PRK14576 |
putative endopeptidase; Provisional |
156-323 |
3.49e-05 |
|
putative endopeptidase; Provisional
Pssm-ID: 173040 [Multi-domain] Cd Length: 405 Bit Score: 45.01 E-value: 3.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 156 IPDNRPLHPQDIINIDLTIYLDGYHGDTSATFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHG 235
Cdd:PRK14576 246 IADTTPAKVGDLIKFDCGIDVAGYGADLARTFVLGEPDKLTQQIYDTIRTGHEHMLSMVAPGVKLKAVFDSTMAVIKTSG 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 236 FS-VNSQISGHGIGkVF---HQPPWIFHDVNSepgKMMPGDCFTIEpclvqgvnsrgdiwddgwTLATRTGARAAQFEHQ 311
Cdd:PRK14576 326 LPhYNRGHLGHGDG-VFlglEEVPFVSTQATE---TFCPGMVLSLE------------------TPYYGIGVGSIMLEDM 383
|
170
....*....|..
gi 50260954 312 VLITDDGVEILS 323
Cdd:PRK14576 384 ILITDSGFEFLS 395
|
|
| PRK10879 |
PRK10879 |
proline aminopeptidase P II; Provisional |
83-223 |
5.43e-05 |
|
proline aminopeptidase P II; Provisional
Pssm-ID: 182804 [Multi-domain] Cd Length: 438 Bit Score: 44.72 E-value: 5.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 83 SKEEWGV-RMACRVAADILKRAGHRiVKPGITTAQVDKAIHEMIIEHGA-YPSplgysnYPKSCTTSINNVIVHGIPDNR 160
Cdd:PRK10879 175 SPEEIAVlRRAGEISALAHTRAMEK-CRPGMFEYQLEGEIHHEFNRHGArYPS------YNTIVGSGENGCILHYTENES 247
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 50260954 161 PLHPQDIINIDLTIYLDGYHGDTSATF-VLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEI 223
Cdd:PRK10879 248 EMRDGDLVLIDAGCEYKGYAGDITRTFpVNGKFTPAQREIYDIVLESLETSLRLYRPGTSIREV 311
|
|
| PRK15173 |
PRK15173 |
peptidase; Provisional |
156-248 |
2.18e-04 |
|
peptidase; Provisional
Pssm-ID: 185095 [Multi-domain] Cd Length: 323 Bit Score: 42.40 E-value: 2.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 156 IPDNRPLHPQDIINIDLTIYLDGYHGDTSATFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHG 235
Cdd:PRK15173 164 IPSNTKACSGDLIKFDCGVDVDGYGADIARTFVVGEPPEITRKIYQTIRTGHEHMLSMVAPGVKMKDVFDSTMEVIKKSG 243
|
90
....*....|....
gi 50260954 236 F-SVNSQISGHGIG 248
Cdd:PRK15173 244 LpNYNRGHLGHGNG 257
|
|
| PRK14575 |
PRK14575 |
putative peptidase; Provisional |
156-248 |
3.14e-04 |
|
putative peptidase; Provisional
Pssm-ID: 173039 [Multi-domain] Cd Length: 406 Bit Score: 42.00 E-value: 3.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 156 IPDNRPLHPQDIINIDLTIYLDGYHGDTSATFVLPEVDKLGRELVSATQEALDLGIRVCKPGVQISEIGKVIGEFSKRHG 235
Cdd:PRK14575 247 IPSNTKACSGDLIKFDCGVDVDGYGADIARTFVVGEPPEITRKIYQTIRTGHEHMLSMVAPGVKMKDVFDSTMEVIKKSG 326
|
90
....*....|....
gi 50260954 236 F-SVNSQISGHGIG 248
Cdd:PRK14575 327 LpNYNRGHLGHGNG 340
|
|
| crvDNA_42K |
TIGR00495 |
42K curved DNA binding protein; Proteins identified by this model have been identified in a ... |
147-245 |
6.08e-04 |
|
42K curved DNA binding protein; Proteins identified by this model have been identified in a number of species as a nuclear (but not nucleolar) protein with a cell cycle dependence. Various names given to members of this family have included cell cycle protein p38-2G4, DNA-binding protein GBP16, and proliferation-associated protein 1. This protein is closely related to methionine aminopeptidase, a cobolt-binding protein. [Unknown function, General]
Pssm-ID: 273105 Cd Length: 390 Bit Score: 41.03 E-value: 6.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50260954 147 SINNVIVHGIP----DNRPLHPQDIINIDLTIYLDGYHGDTSATFVL---PEVDKLGR--ELVSATQEALDLGIRVCKPG 217
Cdd:TIGR00495 83 SVNNCVGHFSPlksdQDYILKEGDVVKIDLGCHIDGFIALVAHTFVVgvaQEEPVTGRkaDVIAAAHLAAEAALRLVKPG 162
|
90 100
....*....|....*....|....*...
gi 50260954 218 VQISEIGKVIGEFSKRHGFSVNSQISGH 245
Cdd:TIGR00495 163 NTNTQVTEAINKVAHSYGCTPVEGMLSH 190
|
|
|