retinal guanylyl cyclase 2 may play a specific role in rods and/or cones of photoreceptors, its activity appears modulated by the calmodulin-like Ca(2+)-binding protein GCAP2
retinal guanylyl cyclase 2 may play a specific role in rods and/or cones of photoreceptors, its activity appears modulated by the calmodulin-like Ca(2+)-binding protein GCAP2
Name, label and taxonomic scope
Tax. Exp
Metazoa
Name
retinal guanylyl cyclase 2
Label
retinal guanylyl cyclase 2 may play a specific role in rods and/or cones of photoreceptors, its activity appears modulated by the calmodulin-like Ca(2+)-binding protein GCAP2
Supporting evidence
Comments
from 10157185: also called RETGC-2, guanylate cyclase 2F, retinal, guanylate cyclase F, GC-F, rod outer segment membrane guanylate cyclase 2, or ROS-GC2
cd06371: PBP1_sensory_GC_DEF_like : Ligand-binding domain of membrane guanylyl cyclases (GC-D, GC-E, and GC-F) that are specifically expressed in sensory tissues
PMID 7777544: Cloning and expression of a second photoreceptor-specific membrane retina guanylyl cyclase (RetGC), RetGC-2.
PMID 7831337: Two membrane forms of guanylyl cyclase found in the eye.
PMID 9175772: Structural and functional characterization of a second subfamily member of the calcium-modulated bovine rod outer segment membrane guanylate cyclase, ROS-GC2.
The protein kinase superfamily is mainly composed of the catalytic domains of serine/threonine-specific and tyrosine-specific protein kinases. It also includes RIO kinases, which are atypical serine protein kinases, aminoglycoside phosphotransferases, and choline kinases. These proteins catalyze the transfer of the gamma-phosphoryl group from ATP to hydroxyl groups in specific substrates such as serine, threonine, or tyrosine residues of proteins.