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hybrid sensor histidine kinase/response regulator

two-component hybrid sensor histidine kinase/response regulator with GAF sensor and HAMP signaling domains

Arch. IDVersionDate PublishedReview Level
1220141012017-02-03
curated
Arch. ID12201410
Version1
Date Published2017-02-03
Review Level
curated
HAMP: HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domainHAMPTar: Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]TarHAMP: HAMP domain [Signal transduction mechanisms]HAMPHAMP: HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domainHAMPGAF_2: GAF domainGAF_2Obsolete: This domain/cluster is obsoleteObsolete
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Sequences with this architecture
This architecture currently does not link to any protein sequence records.
Name, label and taxonomic scope
Taxonomic scopeNameLabel
All organismshybrid sensor histidine kinase/response regulatortwo-component hybrid sensor histidine kinase/response regulator with GAF sensor and HAMP signaling domains
Name, label and taxonomic scope
Tax. ExpAll organisms
Namehybrid sensor histidine kinase/response regulator
Labeltwo-component hybrid sensor histidine kinase/response regulator with GAF sensor and HAMP signaling domains
Supporting evidence
Comments
  • no functional information available; contains histidine kinase and receiver domain, GAF domain and multiple HAMP domains at the N-terminus
Protein Accession
  • ELS53127: putative Two-component system sensor kinase [Streptomyces viridochromogenes Tue57]
  • EGG49306: Two-component hybrid sensor and regulator [Streptomyces griseoaurantiacus M045]
  • CCH15383: hybrid sensory histidine kinase in two-component regulatory system with GAF sensor [Micromonospora lupini str. Lupac 08]
CDD
  • COG2770: HAMP : HAMP domain [Signal transduction mechanisms]
  • smart00304: HAMP : HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
  • pfam13185: GAF_2 : GAF domain
  • smart00388: HisKA : His Kinase A (phosphoacceptor) domain
  • smart00387: HATPase_c : Histidine kinase-like ATPases
  • cd00156: REC : Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR,...
Gene IDs
Conserved domains in this architecture
AccessionShort nameTitle
COG0840TarMethyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]
COG2770HAMPHAMP domain [Signal transduction mechanisms]
cl28304ObsoleteThis domain/cluster is obsolete
pfam13185GAF_2GAF domain
smart00304HAMPHAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain

    HHS Vulnerability Disclosure