1PTH: The Structural Basis Of Aspirin Activity Inferred From The Crystal Structure Of Inactivated Prostaglandin H2 Synthase

PDB ID: 1PTHDownload
MMDB ID: 50885
PDB Deposition Date: 1995/4/11
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 3.4  Å
Source Organism:
Similar Structures:
Biological Unit for 1PTH: dimeric; determined by author and by software (PISA)
Molecular Components in 1PTH
Label Count Molecule
Proteins (2 molecules)
2
Prostaglandin H2 Synthase-1
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
8
N-Acetyl-D-GlucosamineN-Acetyl-D-Glucosamine
2
2
B-OctylglucosideB-Octylglucoside
3
2
Protoporphyrin Ix Containing FeHeme
4
2
2-Hydroxybenzoic AcidSalicylic Acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303