|
Name |
Accession |
Description |
Interval |
E-value |
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
7-744 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 1269.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 7 FHDLPLEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYE 86
Cdd:TIGR01061 1 IFNKPLEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 87 AMVRMSQDWKVRNVLIEMHGNNGSIDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPNLL 166
Cdd:TIGR01061 81 AMVRMSQDWKNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 167 VNGSTGISAGYATDIPPHHLGEVIDAVIKRIQMPSCSVDELMEVIKGPDFPTGGIIQGVDGIRKAYETGKGKIIIRGKAE 246
Cdd:TIGR01061 161 INGATGIAAGYATNIPPHNLNEVIDALIYRIDHPNCSVDKLMEIVKGPDFPTGGIIQGEDGISKAYETGKGKFIIRAKIE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 247 IETIRGGREQIVITEIPFEVNKANLVKKMDEFRIDKKVEGISEVRDETDRTGLRVVIELKKEADAKGILNFLYKNTDLQI 326
Cdd:TIGR01061 241 IEVNKNGLNQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDESDRNGIRIIIELKKDANAEKILNFLFKHTDLQI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 327 TYNFNMVAIHNRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIRSSSDKRDAKN 406
Cdd:TIGR01061 321 NYNFNMVAIANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDKSDAKE 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 407 NLIAKYEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLKALKKKYADTRRSVIE 486
Cdd:TIGR01061 401 NLIDNFKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQIIASEKARNKLLKKQLEEYKKQFAQQRRSQIE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 487 EKIEEIKINLEVMVASEDVYVTVTKDGYLKRTSQRSFAASNGQDFGMKDTDRMLHQFEMNTTDVLLLFTNKGSYIYCPVH 566
Cdd:TIGR01061 481 DFINQIKINESELIENEDYYVLITKAGYIKRTSNRSFASSKYTDFGSKDDDILFAQTIANTTDQILIFTSLGNIINIPVH 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 567 QLPDIRWKDMGQHFSNLITIDRDETIVKAIPIKEFD-PSAYLLFFTKNGMVKKTELTHYKAQRYSKALVALNLKGEDELI 645
Cdd:TIGR01061 561 KLADIRWKDLGEHLSNKITFDENETIVFVGTMNEFDvDQPILVLASKLGMVKRIELTELNIKRNSKATLCIKLKDKDHLI 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 646 DVHVTNGESQIFMATHLGYGLWFGEDEVNVVGARAAGVKGINLKEDDFVVSGEILQQSDSIVLFTQRGAVKRMSLSEFEK 725
Cdd:TIGR01061 641 SAFLQQKDKLICLVSDLGYALVFHTNEIPVVGAKAAGVKGMKLKEDDQVKSGVIFEANESLVLLTQRGSVKRLSISELVV 720
|
730
....*....|....*....
gi 239938679 726 TSRAKRGVVMLrELKKNPH 744
Cdd:TIGR01061 721 TSRAATGKKLL-PLKKKPH 738
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-800 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1217.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 1 MSQPEL---FHDLPLEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYH 77
Cdd:COG0188 1 MSDPPPaerIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 78 PHGDSSVYEAMVRMSQDWKVRNVLIEMHGNNGSIDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVV 157
Cdd:COG0188 81 PHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 158 LPAMFPNLLVNGSTGISAGYATDIPPHHLGEVIDAVIKRIQMPSCSVDELMEVIKGPDFPTGGIIQGVDGIRKAYETGKG 237
Cdd:COG0188 161 LPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 238 KIIIRGKAEIETIRGGREQIVITEIPFEVNKANLVKKMDEFRIDKKVEGISEVRDETDRTGLRVVIELKKEADAKGILNF 317
Cdd:COG0188 241 SIRVRAKAEIEELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLNQ 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 318 LYKNTDLQITYNFNMVAIHNRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIRS 397
Cdd:COG0188 321 LYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIRA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 398 SSDKRDAKNNLIAKYEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLKALKKKY 477
Cdd:COG0188 401 SKDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIKKKY 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 478 ADTRRSVieEKIEEIKINLEVMVASEDVYVTVTKDGYLKRTSQRSFAASNG-----QDFGMKDTDRMLHQFEMNTTDVLL 552
Cdd:COG0188 481 GDERRTE--IEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRggkgvSGMGTKEEDFVEHLFVASTHDTLL 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 553 LFTNKGSYIYCPVHQLPDIRWKDMGQHFSNLITIDRDETIVKAIPIKEFDPSAYLLFFTKNGMVKKTELTHYKAQRySKA 632
Cdd:COG0188 559 FFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKKTPLSDFSNIR-KNG 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 633 LVALNLKGEDELIDVHVTNGESQIFMATHLGYGLWFGEDEVNVVGARAAGVKGINLKEDDFVVSGEILQQSDSIVLFTQR 712
Cdd:COG0188 638 IIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTARGVRGIRLKEGDEVVGMAVVDEEDDLLTVTEN 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 713 GAVKRMSLSEFEKTSRAKRGVVMLRELKKNPHrVVALFACGLEQRLMAETEKGDRKELQTKELRTNDRYSNGSFFFDEEE 792
Cdd:COG0188 718 GYGKRTPLSEYRLQGRGGKGVITIKLTEKNGK-LVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQGVRLIRLDE 796
|
....*...
gi 239938679 793 SGKVTAVW 800
Cdd:COG0188 797 GDKVVSVA 804
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
1-745 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 1090.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 1 MSQPELFHDLPLEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHG 80
Cdd:PRK05561 4 MSMLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPHG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 81 DSSVYEAMVRMSQDWKVRNVLIEMHGNNGSIDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPA 160
Cdd:PRK05561 84 DSSIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLPA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 161 MFPNLLVNGSTGISAGYATDIPPHHLGEVIDAVIKRIQMPSCSVDELMEVIKGPDFPTGG-IIQGVDGIRKAYETGKGKI 239
Cdd:PRK05561 164 RFPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEFVPGPDFPTGGeIITGRDGIRKAYETGRGSI 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 240 IIRGKAEIETIRGGREQIVITEIPFEVNKANLVKKMDEFRIDKKVEGISEVRDETDRTG-LRVVIELKKE-ADAKGILNF 317
Cdd:PRK05561 244 RVRARWEIEDLAGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENpVRIVIEPKSNrVDPEALMNH 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 318 LYKNTDLQITYNFNMVAIH-NRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIR 396
Cdd:PRK05561 324 LFATTDLESSYRVNMNAIGlDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRIIR 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 397 SSSdkrDAKNNLIAKYEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLKALKKK 476
Cdd:PRK05561 404 ESD---EPKANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKELKADAKK 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 477 YADTRRSVIEEKIEEIKINLEVMVASEDVYVTVTKDGYLKRTSQRSFAASngqDFGMKDTDRMLHQFEMNTTDVLLLFTN 556
Cdd:PRK05561 481 FGDPRRTPIEEAEEAIAIDEEALIPDEPVTVVLSKKGWVRRAKGHSIDAS---GLSFKEGDSLLFAFEARTTDKLLLFTS 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 557 KGSYIYCPVHQLPDIRwKDmGQHFSNLITIDRDETIVKAIPikeFDPSAYLLFFTKNGMVKKTELTHyKAQRYSKALVAL 636
Cdd:PRK05561 558 TGRVYSLPVHELPSAR-GD-GEPLTGLVDLAPGEEIVHVLA---FDPDQKLLLASSAGYGFVVTLED-LVARTRAGKAVI 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 637 NLKGEDELIDVHVTNGESQIFMATHLGYGLWFGEDEVNVVGaRAAGVKGINLK-EDDFVVSGEILQQSDSIVLFTQRGAV 715
Cdd:PRK05561 632 NLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPLSELPELG-KGKGVKLINLPkDDDGLVDLRVLNPEDGLVLLTAGKRK 710
|
730 740 750
....*....|....*....|....*....|..
gi 239938679 716 KRMSLSEFEK--TSRAKRGVVMLRELKKNPHR 745
Cdd:PRK05561 711 LKLKPSELEKyrGKRARRGRLLPRGLKRVPRF 742
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
29-473 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 675.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 29 QDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKVRNVLIEMHGNN 108
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 109 GSIDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPNLLVNGSTGISAGYATDIPPHHLGE 188
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 189 VIDAVIKRIQMPSCSVDELMEVIKGPDFPTGGIIQGVDGIRKAYETGKGKIIIRGKAEIETIRgGREQIVITEIPFEVNK 268
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDE-GRNTIEITELPYQVNK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 269 ANLVKKMDEFRIDKKVEGISEVRDETDRTGLRVVIELKKEADAKGILNFLYKNTDLQITYNFNMVAI-HNRRPMLMSLPS 347
Cdd:cd00187 240 AKLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFdPNGRPKKLNLKE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 348 ILDAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIRSSSdkrDAKNNLIAKYE---FTEPQAEAIVS 424
Cdd:cd00187 320 ILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSSD---EAKKALIEELEklgFSEIQADAILD 396
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 239938679 425 LQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLKAL 473
Cdd:cd00187 397 MRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
10-463 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 621.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 10 LPLEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMV 89
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 90 RMSQDWKVRNVLIEMHGNNGSI-DGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPNLLVN 168
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 169 GSTGISAGYATDIPPHHLGEVIDAVIKRIQMPSCSVDELMEVIKGPDFPTGGIIQgvdgirkayetGKGKIIIRGKAEIE 248
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 249 TirggREQIVITEIPFEVNKANLVKKMDEFRIDKKVEGISEVRDET-DRTGLRVVIELKKEADAKGILNFLYKNTDLQIT 327
Cdd:smart00434 230 D----DNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQTT 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 328 YNFNMVAIH-NRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKAK-DRHHIVEGLMKALSILDEVIATIRSSSDKR-DA 404
Cdd:smart00434 306 FSINMLALFdNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDLAkEA 385
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 239938679 405 KNNLIAKYEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLL 463
Cdd:smart00434 386 KEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
31-471 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 605.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 31 RALPDARDGLKPVQRRILYAMHtDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKVRNVLIEMHGNNGS 110
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMF-ELLNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 111 -IDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPNLLVNGSTGISAGYATDIPPHHLGEV 189
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 190 IDAVIKRIQMPSCSVdeLMEVIKGPDFPTGGIIQGVDGIRKAYETGKGKIIIRGKAEIETirggREQIVITEIPFEVNKA 269
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED----RKTIVITELPYGVWTS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 270 NLVKKMDEFRIDKKVEGISEVRDETDRtGLRVVIELKKEADAKGILNFLYKNTDLQITYNFNMVAIHNRRPMLMSLPSIL 349
Cdd:pfam00521 234 DLIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEIL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 350 DAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIRSSSDKRDAKNNLIAkyEFTEPQAEAIVSLQLYR 429
Cdd:pfam00521 313 KEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIE--ELSEIQADYLLDMRLRR 390
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 239938679 430 LTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLK 471
Cdd:pfam00521 391 LTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
23-121 |
1.20e-35 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 146.02 E-value: 1.20e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 23 YSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKVRNVLI 102
Cdd:NF038098 18 YAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSYVKCARVVAETMGNYHPHGDSSIYDTLVRMAQPWSLRYPLV 97
|
90
....*....|....*....
gi 239938679 103 EMHGNNGSIDGDPPAAMRY 121
Cdd:NF038098 98 DGQGNFGSPGNDPAAAMRY 116
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
7-744 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 1269.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 7 FHDLPLEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYE 86
Cdd:TIGR01061 1 IFNKPLEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 87 AMVRMSQDWKVRNVLIEMHGNNGSIDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPNLL 166
Cdd:TIGR01061 81 AMVRMSQDWKNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 167 VNGSTGISAGYATDIPPHHLGEVIDAVIKRIQMPSCSVDELMEVIKGPDFPTGGIIQGVDGIRKAYETGKGKIIIRGKAE 246
Cdd:TIGR01061 161 INGATGIAAGYATNIPPHNLNEVIDALIYRIDHPNCSVDKLMEIVKGPDFPTGGIIQGEDGISKAYETGKGKFIIRAKIE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 247 IETIRGGREQIVITEIPFEVNKANLVKKMDEFRIDKKVEGISEVRDETDRTGLRVVIELKKEADAKGILNFLYKNTDLQI 326
Cdd:TIGR01061 241 IEVNKNGLNQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDESDRNGIRIIIELKKDANAEKILNFLFKHTDLQI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 327 TYNFNMVAIHNRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIRSSSDKRDAKN 406
Cdd:TIGR01061 321 NYNFNMVAIANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDKSDAKE 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 407 NLIAKYEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLKALKKKYADTRRSVIE 486
Cdd:TIGR01061 401 NLIDNFKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQIIASEKARNKLLKKQLEEYKKQFAQQRRSQIE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 487 EKIEEIKINLEVMVASEDVYVTVTKDGYLKRTSQRSFAASNGQDFGMKDTDRMLHQFEMNTTDVLLLFTNKGSYIYCPVH 566
Cdd:TIGR01061 481 DFINQIKINESELIENEDYYVLITKAGYIKRTSNRSFASSKYTDFGSKDDDILFAQTIANTTDQILIFTSLGNIINIPVH 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 567 QLPDIRWKDMGQHFSNLITIDRDETIVKAIPIKEFD-PSAYLLFFTKNGMVKKTELTHYKAQRYSKALVALNLKGEDELI 645
Cdd:TIGR01061 561 KLADIRWKDLGEHLSNKITFDENETIVFVGTMNEFDvDQPILVLASKLGMVKRIELTELNIKRNSKATLCIKLKDKDHLI 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 646 DVHVTNGESQIFMATHLGYGLWFGEDEVNVVGARAAGVKGINLKEDDFVVSGEILQQSDSIVLFTQRGAVKRMSLSEFEK 725
Cdd:TIGR01061 641 SAFLQQKDKLICLVSDLGYALVFHTNEIPVVGAKAAGVKGMKLKEDDQVKSGVIFEANESLVLLTQRGSVKRLSISELVV 720
|
730
....*....|....*....
gi 239938679 726 TSRAKRGVVMLrELKKNPH 744
Cdd:TIGR01061 721 TSRAATGKKLL-PLKKKPH 738
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-800 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1217.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 1 MSQPEL---FHDLPLEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYH 77
Cdd:COG0188 1 MSDPPPaerIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 78 PHGDSSVYEAMVRMSQDWKVRNVLIEMHGNNGSIDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVV 157
Cdd:COG0188 81 PHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 158 LPAMFPNLLVNGSTGISAGYATDIPPHHLGEVIDAVIKRIQMPSCSVDELMEVIKGPDFPTGGIIQGVDGIRKAYETGKG 237
Cdd:COG0188 161 LPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 238 KIIIRGKAEIETIRGGREQIVITEIPFEVNKANLVKKMDEFRIDKKVEGISEVRDETDRTGLRVVIELKKEADAKGILNF 317
Cdd:COG0188 241 SIRVRAKAEIEELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLNQ 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 318 LYKNTDLQITYNFNMVAIHNRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIRS 397
Cdd:COG0188 321 LYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIRA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 398 SSDKRDAKNNLIAKYEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLKALKKKY 477
Cdd:COG0188 401 SKDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIKKKY 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 478 ADTRRSVieEKIEEIKINLEVMVASEDVYVTVTKDGYLKRTSQRSFAASNG-----QDFGMKDTDRMLHQFEMNTTDVLL 552
Cdd:COG0188 481 GDERRTE--IEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRggkgvSGMGTKEEDFVEHLFVASTHDTLL 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 553 LFTNKGSYIYCPVHQLPDIRWKDMGQHFSNLITIDRDETIVKAIPIKEFDPSAYLLFFTKNGMVKKTELTHYKAQRySKA 632
Cdd:COG0188 559 FFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKKTPLSDFSNIR-KNG 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 633 LVALNLKGEDELIDVHVTNGESQIFMATHLGYGLWFGEDEVNVVGARAAGVKGINLKEDDFVVSGEILQQSDSIVLFTQR 712
Cdd:COG0188 638 IIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTARGVRGIRLKEGDEVVGMAVVDEEDDLLTVTEN 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 713 GAVKRMSLSEFEKTSRAKRGVVMLRELKKNPHrVVALFACGLEQRLMAETEKGDRKELQTKELRTNDRYSNGSFFFDEEE 792
Cdd:COG0188 718 GYGKRTPLSEYRLQGRGGKGVITIKLTEKNGK-LVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQGVRLIRLDE 796
|
....*...
gi 239938679 793 SGKVTAVW 800
Cdd:COG0188 797 GDKVVSVA 804
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
1-745 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 1090.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 1 MSQPELFHDLPLEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHG 80
Cdd:PRK05561 4 MSMLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPHG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 81 DSSVYEAMVRMSQDWKVRNVLIEMHGNNGSIDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPA 160
Cdd:PRK05561 84 DSSIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLPA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 161 MFPNLLVNGSTGISAGYATDIPPHHLGEVIDAVIKRIQMPSCSVDELMEVIKGPDFPTGG-IIQGVDGIRKAYETGKGKI 239
Cdd:PRK05561 164 RFPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEFVPGPDFPTGGeIITGRDGIRKAYETGRGSI 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 240 IIRGKAEIETIRGGREQIVITEIPFEVNKANLVKKMDEFRIDKKVEGISEVRDETDRTG-LRVVIELKKE-ADAKGILNF 317
Cdd:PRK05561 244 RVRARWEIEDLAGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENpVRIVIEPKSNrVDPEALMNH 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 318 LYKNTDLQITYNFNMVAIH-NRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIR 396
Cdd:PRK05561 324 LFATTDLESSYRVNMNAIGlDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRIIR 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 397 SSSdkrDAKNNLIAKYEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLKALKKK 476
Cdd:PRK05561 404 ESD---EPKANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKELKADAKK 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 477 YADTRRSVIEEKIEEIKINLEVMVASEDVYVTVTKDGYLKRTSQRSFAASngqDFGMKDTDRMLHQFEMNTTDVLLLFTN 556
Cdd:PRK05561 481 FGDPRRTPIEEAEEAIAIDEEALIPDEPVTVVLSKKGWVRRAKGHSIDAS---GLSFKEGDSLLFAFEARTTDKLLLFTS 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 557 KGSYIYCPVHQLPDIRwKDmGQHFSNLITIDRDETIVKAIPikeFDPSAYLLFFTKNGMVKKTELTHyKAQRYSKALVAL 636
Cdd:PRK05561 558 TGRVYSLPVHELPSAR-GD-GEPLTGLVDLAPGEEIVHVLA---FDPDQKLLLASSAGYGFVVTLED-LVARTRAGKAVI 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 637 NLKGEDELIDVHVTNGESQIFMATHLGYGLWFGEDEVNVVGaRAAGVKGINLK-EDDFVVSGEILQQSDSIVLFTQRGAV 715
Cdd:PRK05561 632 NLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPLSELPELG-KGKGVKLINLPkDDDGLVDLRVLNPEDGLVLLTAGKRK 710
|
730 740 750
....*....|....*....|....*....|..
gi 239938679 716 KRMSLSEFEK--TSRAKRGVVMLRELKKNPHR 745
Cdd:PRK05561 711 LKLKPSELEKyrGKRARRGRLLPRGLKRVPRF 742
|
|
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
23-765 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 959.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 23 YSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKVRNVLI 102
Cdd:PRK05560 21 YAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAVYDALVRMAQDFSMRYPLV 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 103 EMHGNNGSIDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPNLLVNGSTGISAGYATDIP 182
Cdd:PRK05560 101 DGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPNLLVNGSSGIAVGMATNIP 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 183 PHHLGEVIDAVIKRIQMPSCSVDELMEVIKGPDFPTGGIIQGVDGIRKAYETGKGKIIIRGKAEIETIRgGREQIVITEI 262
Cdd:PRK05560 181 PHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMRAKAEIEEIK-GREAIIVTEI 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 263 PFEVNKANLVKKMDEFRIDKKVEGISEVRDETDRTGLRVVIELKKEADAKGILNFLYKNTDLQITYNFNMVAIHNRRPML 342
Cdd:PRK05560 260 PYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDGMRIVIELKRDAVPEVVLNNLYKHTQLQTSFGINMLALVDGQPKL 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 343 MSLPSILDAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIRSSSDKRDAKNNLIAKYEFTEPQAEAI 422
Cdd:PRK05560 340 LNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTPAEAKEGLMERFGLSEIQAQAI 419
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 423 VSLQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLKALKKKYADTRRSVieEKIEEIKINLEVMVAS 502
Cdd:PRK05560 420 LDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGDPRRTE--IIEGEGDIDDEDLIPE 497
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 503 EDVYVTVTKDGYLKRTSQRSFAASN----G-QDFGMKDTDRMLHQFEMNTTDVLLLFTNKGSyIYC-PVHQLPDIRWKDM 576
Cdd:PRK05560 498 EDVVVTLTHGGYIKRTPLDEYRAQRrggkGvSGAKTKEDDFVEHLFVASTHDTLLFFTNRGR-VYRlKVYEIPEASRTAR 576
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 577 GQHFSNLITIDRDETIVKAIPIKEFDPSAYLLFFTKNGMVKKTELTHYKAQRySKALVALNLKGEDELIDVHVTNGESQI 656
Cdd:PRK05560 577 GRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIR-SNGIIAINLDEGDELIGVRLTDGDDDI 655
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 657 FMATHLGYGLWFGEDEVNVVGARAAGVKGINLKEDDFVVSGEILQQSDSIVL-FTQRGAVKRMSLSEFEKTSRAKRGVVM 735
Cdd:PRK05560 656 LLATKNGKAIRFPESDVRPMGRTARGVRGIKLREGDEVVSMDVVREDSQEILtVTENGYGKRTPVSEYRLQGRGGKGVIT 735
|
730 740 750
....*....|....*....|....*....|
gi 239938679 736 LRELKKNpHRVVALFACGLEQRLMAETEKG 765
Cdd:PRK05560 736 IKITEKN-GKLVGALPVDDDDEIMLITDSG 764
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
12-802 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 868.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 12 LEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMVRM 91
Cdd:TIGR01063 6 IEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYDTLVRM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 92 SQDWKVRNVLIEMHGNNGSIDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPNLLVNGST 171
Cdd:TIGR01063 86 AQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLLVNGSS 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 172 GISAGYATDIPPHHLGEVIDAVIKRIQMPSCSVDELMEVIKGPDFPTGGIIQGVDGIRKAYETGKGKIIIRGKAEIETIR 251
Cdd:TIGR01063 166 GIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAEIEEDS 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 252 GGREQIVITEIPFEVNKANLVKKMDEFRIDKKVEGISEVRDETDRTGLRVVIELKKEADAKGILNFLYKNTDLQITYNFN 331
Cdd:TIGR01063 246 KGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREGIRIVIELKRDAVAEVVLNNLYKQTQLQVSFGIN 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 332 MVAIHNRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIRSSSDKRDAKNNLIAK 411
Cdd:TIGR01063 326 MLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAKTRLVER 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 412 YEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLKALKKKYADTRRSViEEKIEE 491
Cdd:TIGR01063 406 FSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPRRTE-IVYDES 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 492 IKINLEVMVASEDVYVTVTKDGYLKRTSQRSFAASNG-----QDFGMKDTDRMLHQFEMNTTDVLLLFTNKGSYIYCPVH 566
Cdd:TIGR01063 485 EDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRggkgvSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVYWLKVY 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 567 QLPDIRWKDMGQHFSNLITIDRDETIVKAIPIKEFDPSAYLLFFTKNGMVKKTELTHYKAQRySKALVALNLKGEDELID 646
Cdd:TIGR01063 565 QIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIR-SNGIIAIKLDDGDELIS 643
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 647 VHVTNGESQIFMATHLGYGLWFGEDEVNVVGARAAGVKGINLKEDDFVVSGEILQQSDSIVLFTQRGAVKRMSLSEFEKT 726
Cdd:TIGR01063 644 VRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIKLKNEDFVVSLLVVSEESYLLIVTENGYGKRTSIEEYRET 723
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 239938679 727 SRAKRGVVMLRELKKNpHRVVALFACGLEQRLMAETEKGDRKELQTKELRTNDRYSNGSFFFDEEESGKVTAVWRL 802
Cdd:TIGR01063 724 SRGGKGVKSIKITDRN-GQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDEDDKLVSVSKV 798
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
10-698 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 724.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 10 LPLEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMV 89
Cdd:PRK13979 16 IPLEEAMPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSSVYDAMV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 90 RMSQDWKVRNVLIEMHGNNGSIDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPNLLVNG 169
Cdd:PRK13979 96 ILAQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPNLLVNG 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 170 STGISAGYATDIPPHHLGEVIDAVIKRIQMPSCSVDELMEVIKGPDFPTGGIIQGVDGIRKAYETGKGKIIIRGKAEIET 249
Cdd:PRK13979 176 AFGIAVGLATNIPPHNLKEVIDGTLAYIDNNEITTKELMNYIKGPDLPTGGILIGKKSLLSAYETGEGKVTLRAKTKIEK 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 250 IRGGREQIVITEIPFEVNKANLVKKMDEFRIDKK----VEGISEVRDETDRTGLRVVIELKKEAD---AKGILNFLYKNT 322
Cdd:PRK13979 256 LENGRLGIVITEFPYRRNKAKLLQTISEMTADKKhskaLENISDIRDESDRNGIRAVIEFKKSADedvAEKVLKYLYKKT 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 323 DLQITYNFNMVAIHNRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIRSSSDKR 402
Cdd:PRK13979 336 DLQCNISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGIMDEIIKTIRSSKSKK 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 403 DAKNNLIAKYEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLKALKKKYADTRR 482
Cdd:PRK13979 416 DASENLIEKFGFTDEQAEAILELMLYRLTGLEIVAFEKEYKELEKLIKKLTKILSSEKELLKVIKKELKEVKEKYGDERR 495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 483 SVIEEKIEEIKINLEVMVASEDVYVTVTKDGYLKRTSQRSFAASNG--QDFGMKDTDRMLHQFEMNTTDVLLLFTNKGSY 560
Cdd:PRK13979 496 TSIIEDDEKAKIDVEELIVVEDVVITLSNEGFIKRIPLKSYNRSNSnvEDIEYREGDFNKFLIQSNTKDTLLIFTDKGNM 575
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 561 IYCPVHQLPDIRWKDMGQHFSNLI-TID-RDETIVKAIPIKEFDPSAYLLFFTKNGMVKKTELTHYKAQrYSKaLVALNL 638
Cdd:PRK13979 576 YQIKGINIPEFKWKEKGERLDEIIkGIDlESEKIIEAYSIEDFTPQKDFIFITDSGGIKKTSLDKFVTN-YTK-LMALKL 653
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 239938679 639 KGEDELIDVHVTNGESQ---IFMATHLGYGLWFGEDEVNVVGARAAGVKGINLKEDDFVVSGE 698
Cdd:PRK13979 654 KKGEKLIKVKLVDRTREekfIKIKTKKGLSFTVEEPELEPVDRNIIGYQLFDLLPNDSIKKVD 716
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
29-473 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 675.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 29 QDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKVRNVLIEMHGNN 108
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 109 GSIDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPNLLVNGSTGISAGYATDIPPHHLGE 188
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 189 VIDAVIKRIQMPSCSVDELMEVIKGPDFPTGGIIQGVDGIRKAYETGKGKIIIRGKAEIETIRgGREQIVITEIPFEVNK 268
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDE-GRNTIEITELPYQVNK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 269 ANLVKKMDEFRIDKKVEGISEVRDETDRTGLRVVIELKKEADAKGILNFLYKNTDLQITYNFNMVAI-HNRRPMLMSLPS 347
Cdd:cd00187 240 AKLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFdPNGRPKKLNLKE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 348 ILDAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIRSSSdkrDAKNNLIAKYE---FTEPQAEAIVS 424
Cdd:cd00187 320 ILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSSD---EAKKALIEELEklgFSEIQADAILD 396
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 239938679 425 LQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLKAL 473
Cdd:cd00187 397 MRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
10-463 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 621.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 10 LPLEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMV 89
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 90 RMSQDWKVRNVLIEMHGNNGSI-DGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPNLLVN 168
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 169 GSTGISAGYATDIPPHHLGEVIDAVIKRIQMPSCSVDELMEVIKGPDFPTGGIIQgvdgirkayetGKGKIIIRGKAEIE 248
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 249 TirggREQIVITEIPFEVNKANLVKKMDEFRIDKKVEGISEVRDET-DRTGLRVVIELKKEADAKGILNFLYKNTDLQIT 327
Cdd:smart00434 230 D----DNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQTT 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 328 YNFNMVAIH-NRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKAK-DRHHIVEGLMKALSILDEVIATIRSSSDKR-DA 404
Cdd:smart00434 306 FSINMLALFdNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDLAkEA 385
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 239938679 405 KNNLIAKYEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLL 463
Cdd:smart00434 386 KEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
31-471 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 605.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 31 RALPDARDGLKPVQRRILYAMHtDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKVRNVLIEMHGNNGS 110
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMF-ELLNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 111 -IDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPNLLVNGSTGISAGYATDIPPHHLGEV 189
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 190 IDAVIKRIQMPSCSVdeLMEVIKGPDFPTGGIIQGVDGIRKAYETGKGKIIIRGKAEIETirggREQIVITEIPFEVNKA 269
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED----RKTIVITELPYGVWTS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 270 NLVKKMDEFRIDKKVEGISEVRDETDRtGLRVVIELKKEADAKGILNFLYKNTDLQITYNFNMVAIHNRRPMLMSLPSIL 349
Cdd:pfam00521 234 DLIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEIL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 350 DAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIRSSSDKRDAKNNLIAkyEFTEPQAEAIVSLQLYR 429
Cdd:pfam00521 313 KEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIE--ELSEIQADYLLDMRLRR 390
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 239938679 430 LTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLK 471
Cdd:pfam00521 391 LTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
10-742 |
9.27e-146 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 445.89 E-value: 9.27e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 10 LPLEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMV 89
Cdd:TIGR01062 4 IDLGNFTEEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYEAMV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 90 RMSQDWKVRNVLIEMHGNNGSIDG-DPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPNLLVN 168
Cdd:TIGR01062 84 LMAQPFSYRYPLVDGQGNWGAPDDpKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNILLN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 169 GSTGISAGYATDIPPHHLGEVIDAVIKRIQMPSCSVDELMEVIKGPDFPTGG-IIQGVDGIRKAYETGKGKIIIRGKAEI 247
Cdd:TIGR01062 164 GTTGIAVGMATDIPPHNLHELADAALYLIDNPKAGLDDILNIVQGPDFPTEAeIIDKAEEIRKIYETGRGSFRMRARWKK 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 248 ETIrggreQIVITEIPFEVNKANLVKKMDEFRIDKKVEGISEVRDETDRTG-LRVVIELK-KEADAKGILNFLYKNTDLQ 325
Cdd:TIGR01062 244 EDG-----QIVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDHENpIRVVIVPRsNRVDPDIVMEHLFATTDLE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 326 ITYNFNMVAI-HNRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIRsssDKRDA 404
Cdd:TIGR01062 319 KSYRLNMNMIgLDNVPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIR---EEDEP 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 405 KNNLIAKYEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLKALKKKYADTRRSV 484
Cdd:TIGR01062 396 KTILMERFKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSELEKERAILEKILKSERELNQLVKKEIQADATKYGLARRSS 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 485 IEEKIEEIKINLEVMVASEDVYVTVTKDGYLKRTSQRSFAASNgqdFGMKDTDRMLHQFEMNTTDVLLLFTNKG-SYIYC 563
Cdd:TIGR01062 476 LEEREEAKQVSEIDMIPKEPVTIILSKMGWVRSAKGHDIDLST---LKYKAGDSEKAIIEGKSNQKVVFIDSTGrSYALD 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 564 PVhQLPDIRwkDMGQHFSNLITIDRDETIVKAIPIKefdPSAYLLFFTKNG---MVKKTELThyKAQRYSKALValNLKG 640
Cdd:TIGR01062 553 PD-NLPSAR--GQGEPLTGKLLLPIGATITNILMYS---PNQLLLMASDAGygfLCNFNDLI--ARNKAGKALI--NLPE 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 641 EDELIDVHVTNGESQIFMA-THLGYGLWFGEDEVNVVgARAAGVKGINLKEDDFVVSGEIL--------QQSDSIVLFTQ 711
Cdd:TIGR01062 623 NASVIAPLPVNGDSDMIAAiTEAGRMLVFPIDDLPEL-SKGKGNKLIRIPSANAKRGEDGLldlkifnkQDGLSWNDGKR 701
|
730 740 750
....*....|....*....|....*....|.
gi 239938679 712 RGAVKRMSLSEFeKTSRAKRGVVMLRELKKN 742
Cdd:TIGR01062 702 KIQLEPEELQKF-LGERGRFGTTLPRGLPKN 731
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
12-483 |
3.32e-73 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 251.55 E-value: 3.32e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 12 LEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHtdgNTFDKNFRKAAKTVGNVIgNYHPHGDSSVYEAMVRM 91
Cdd:PRK09631 4 IKTLFKDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSLF---EMHDGKFHKVANVVGNTM-KYHPHGDASIYEALVNL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 92 SQdwkvRNVLIEMHGNNGSI-DGDPPAAMRYTEARLSPIASELLrdIDKNTVEFVPNFDDTSKEPVVLPAMFPNLLVNGS 170
Cdd:PRK09631 80 AN----KDLFIDKQGNFGNLfTGDPASAARYIECRLTPLAKEVL--YNKEITEYEPSYDGRNNEPLCLPAKIPVILIQGA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 171 TGISAGYATDIPPHHLGEVIDAVIKRIQmpscsvDELMEVIkgPDFPTGGIIQGVDgirkaYETGKGKIIIRgkAEIETI 250
Cdd:PRK09631 154 EGIAVGMATKILPHNFNEILQAVKSELL------GESFALY--PDFPTGGIVDVSE-----YADGNGKVLVR--AKIETK 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 251 RGGReqIVITEIPFEVNKANLVKKMDEFRIDKKVEgISEVrdeTDRTGLRVVIELK--KEADAKGILNFLYKNTDLQITY 328
Cdd:PRK09631 219 DEKT--IVIREIPFGTTTESLIASIEKAARKGKIK-ISSI---NDYTAENVEIEIKlpRGVYASEVIEALYAYTDCEVSI 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 329 NFNMVAIHNRRPMLMSLPSILDAYIGHQKEVVTNRsvYELQKAKDRHHIVEGLMKALSI---LDEVIATIRSSSDKRDAK 405
Cdd:PRK09631 293 SVNLLVIKDRYPVIYTVTDIIKFHAEHLQKVLKME--LELERAKLLEKIFAKTLEQIFIeerIYKRIETISSEEDVISIV 370
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 406 NNLIAKY------EFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNdkkLLKVITNSLKALKKKYAD 479
Cdd:PRK09631 371 LSELKPFkeelsrDVTEEDIENLLKIPIRRISLFDIDKNQKEIRILNKELKSVEKNLKS---IKGYAINFIDKLLAKYSK 447
|
....*.
gi 239938679 480 --TRRS 483
Cdd:PRK09631 448 eyPRKT 453
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
18-481 |
2.40e-50 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 190.60 E-value: 2.40e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 18 DRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHT--DGNtfdknFRKAAKTVGNVIgNYHPHGDSSVYEAMVRMSQdw 95
Cdd:PRK12758 29 NWFLDYASYVILERAVPHIEDGLKPVQRRILHSMKEmdDGR-----YNKVANVVGHTM-QYHPHGDASIGDALVQLGQ-- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 96 kvRNVLIEMHGNNGSI-DGDPPAAMRYTEARLSPIASELLrdIDKNTVEFVPNFDDTSKEPVVLPAMFPNLLVNGSTGIS 174
Cdd:PRK12758 101 --KDLLIDTQGNWGNIlTGDGAAAPRYIEARLSKFALEVV--FNPKTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIA 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 175 AGYATDIPPHHLGEVIDAVIKRIQmpscsvDELMEVIkgPDFPTGGIIQgvdgiRKAYETGK--GKIIIRGKAEIETirg 252
Cdd:PRK12758 177 VGLSTKILPHNFNELIDASIAYLK------GKEFKLY--PDFPTGGIID-----VSNYNDGErgGRVRVRAKIEKLD--- 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 253 gREQIVITEIPFEVNKANL----VKKMDEFRID-KKVEgisevrdetDRTGLRVVIELK--------KEADAkgilnfLY 319
Cdd:PRK12758 241 -KKTLVITEIPYGTTTSSLidsiLKANDKGKIKiKKVE---------DNTAADVEILVHlapgvspdKTIDA------LY 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 320 KNTDLQITYNFNMVAIHNRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKAKDRHH--------IVEGLMKAL---SIL 388
Cdd:PRK12758 305 AFTDCEVSISPNACVIIDNKPHFLGVSDILRRSTDHTVSLLKQELEIRLSELEEQWHfaslekifIEERIYKEIeeaETW 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 389 DEVIATIrsssDKRDA--KNNLIAkyEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNdkkLLKVI 466
Cdd:PRK12758 385 EAVIEAI----DKGLEpfKKQFIR--EVTEDDIVRLTEIKIKRISKFDSDKADELIARLEAEIAEVKHHLAH---LTDYA 455
|
490
....*....|....*
gi 239938679 467 TNSLKALKKKYADTR 481
Cdd:PRK12758 456 IAYFTNLKKKYGKGR 470
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
12-477 |
1.81e-46 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 173.16 E-value: 1.81e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 12 LEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTdgnTFDKNFRKAAKTVGNVIGnYHPHGDSSVYEAMVRM 91
Cdd:PRK09630 4 VSDLFKTHFMHYASYVILERAIPHILDGLKPVQRRLLWTLFR---MDDGKMHKVANIAGRTMA-LHPHGDAPIVEALVVL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 92 SQdwkvRNVLIEMHGNNGS-IDGDPPAAMRYTEARLSPIASELLRDIDknTVEFVPNFDDTSKEPVVLPAMFPNLLVNGS 170
Cdd:PRK09630 80 AN----KGYLIDTQGNFGNpLTGDPHAAARYIEARLSPLAKEVLFNTD--LMTFHDSYDGREKEPDILPAKLPLLLLHGV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 171 TGISAGYATDIPPHHLGEVIDAVIKRIQmpscsvDELMEVIkgPDFPTGGIIQGVDgirkaYETGKGKIIIRgkAEIETI 250
Cdd:PRK09630 154 DGIAVGMTTKIFPHNFCELLEAQIAILN------DQPFTLL--PDFPSGGTMDASE-----YQDGLGSITLR--ASIDII 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 251 rgGREQIVITEIPFEVNKANLVKKMdEFRIDKKVEGISEVRD-ETDRTglRVVIELKKEADAKGILNFLYKNTDLQITYN 329
Cdd:PRK09630 219 --NDKTLLIKEICPSTTTETLIRSI-ENAAKRGIIKIDSIQDfSTDLP--HIEIKLPKGIYAKDLLRPLFTHTECQVILT 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 330 FNMVAIHNRRPMLMSLPSILDAyighQKEVVTNRSVYELQKAKDR------HHIVEGLMKALSILDEV------IATIRS 397
Cdd:PRK09630 294 SRPTAIYQNKPVETSISEILRL----HTETLQGYLKKELLILEDSlsrehyHKTLEYIFIKHKLYDTVremlskRKTSPS 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 398 SSDKRDAKNNLIAKYEFTEP-----QAEA-IVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNDKkllKVITNSLK 471
Cdd:PRK09630 370 SSDLHNAVLEALTPFLDTLPtpvdkQATAqLASLTIKKILCFNENSYTKELACIEKKQAAVQKDLSQLK---KYTVKYLK 446
|
....*.
gi 239938679 472 ALKKKY 477
Cdd:PRK09630 447 GLLETY 452
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
7-475 |
2.96e-43 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 162.92 E-value: 2.96e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 7 FHDLPLEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYA----MHTDGNTFDKNfrkAAKTVGNVIGNYHpHGDS 82
Cdd:PHA02592 3 LKERSLKSIVNNEALEYAMYTVEERAIPNLIDGLKPVQRFVIHRaleyAKGNKEKFDKV---AAIAGGVADLGYH-HGET 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 83 SVYEAMVRMSQDWKVRNVLIEMHGNNGSIDGDPPAAMRYTEARLSPIASELLRDIDkntveFVPNF-DDTSKEPVVLPAM 161
Cdd:PHA02592 79 SAQDAGALMANTWNNNIPLLDGQGNFGSRLVQKAAAARYIFARVHDNFRKIYKDED-----LAPVHeDPEHIPPAFYLPI 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 162 FPNLLVNGSTGISAGYATDIPPHHLGEVIDAVIKRIQmpSCSVDELmeVIKGPDFpTGGIIqgvdgirkayETGKGKIII 241
Cdd:PHA02592 154 IPMVLLNGVSGIATGYATNILPHSPKSVIKAVLAALN--GKDITEP--KVQFPEF-KGEVV----------EIEPGSYEI 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 242 RGKAEIEtirgGREQIVITEIPFEVNKANLVKKMDEFrIDKKVegISEVRDETDRtGLRVVIELKKEADAKGILNFLYKN 321
Cdd:PHA02592 219 RGTYELN----GKTKLHITEIPVKYDRETYVAVLDPL-EEKGK--IVSYDDCTED-GFRFKVTLKREENEEATHEKIMKD 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 322 TDLQITYNFNMVAIhNRRPMLMSLPS----ILDaYIGHQKEVVTNRSVYELQKAKDRhhivegLMKALS---ILDEVIAT 394
Cdd:PHA02592 291 FGLIERVSQNITVI-NENGKLKVYENaedlIRD-FVEIRKTYVQKRIQYEIKETEEA------FDLALAkaeFIKRVIAG 362
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 395 IRSSSDK-RDAKNNLIAKYEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESilSNDKKLlkvITNSLKAL 473
Cdd:PHA02592 363 EIVLQGKtRSELTEELSDNKDFGEYADKLVAMNIYSMTSDEREKLQKEAEELEKEHEYWKK--TTAKKE---YIKDLEEL 437
|
..
gi 239938679 474 KK 475
Cdd:PHA02592 438 KK 439
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
23-121 |
1.20e-35 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 146.02 E-value: 1.20e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 23 YSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKVRNVLI 102
Cdd:NF038098 18 YAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSYVKCARVVAETMGNYHPHGDSSIYDTLVRMAQPWSLRYPLV 97
|
90
....*....|....*....
gi 239938679 103 EMHGNNGSIDGDPPAAMRY 121
Cdd:NF038098 98 DGQGNFGSPGNDPAAAMRY 116
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
31-483 |
5.90e-22 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 102.05 E-value: 5.90e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 31 RALPDARDGLKPVQRRILYAMhtdgntFDKNFRKAAKtVGNVIG------NYHpHGDSSVYEAMVRMSQDWKVRN--VLI 102
Cdd:PTZ00108 680 RSIPSLVDGLKPGQRKILFAC------FKRNLKNEIK-VAQLSGyvsehsAYH-HGEQSLQQTIVGMAQNFVGSNniNLL 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 103 EMHGNNGS--IDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVpNFDDTSKEPVVLPAMFPNLLVNGSTGISAGYATD 180
Cdd:PTZ00108 752 YPCGQFGSrlQGGKDHAAARYIFTKLSKITRYIFPEEDDPILDYL-EDDGQSVEPFYYVPIIPMVLVNGAEGIGTGFSTS 830
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 181 IPPHHLGEVIDAVIKRIqmpscSVDELMEVI---KGPDfptgGIIQgvdgirkayETGKGKIIIRGKAEIEtirgGREQI 257
Cdd:PTZ00108 831 IPNYNPLDIIDNLRRRL-----NGEEVRPLVpwyRGFK----GTIE---------RNPKGKFISKGIYEKV----PDGTV 888
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 258 VITEIPFEVNKANLvKKMDEFRIDKKVEGISEVRDETdrTGLRVVIELK------KEADAKGILNFLYKNTDLQITynfN 331
Cdd:PTZ00108 889 EITELPIGKWTEDY-KEFLESETLKEKDVIVDYRDYS--TANTVHFTVKlndgvlEQWEEEGIEKVFKLKSTISTT---N 962
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 332 MVAI--HNRRPMLMSLPSILDAYIGHQKEVVTNRSVY---ELQKAKDR--------HHIVEG-----------LMKALS- 386
Cdd:PTZ00108 963 MVLFdeNGKIKKYSDALDILKEFYLVRLDLYKKRKEYllgKLERELARlsnkvrfiKHVINGelvitnakkkdLVKELKk 1042
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 387 --------ILDEVIATIRSSSDKRDAKNNLIAKYEFTEPQAEA-----IVSLQLYRLTNTDITALKEEAEELGKKIEELE 453
Cdd:PTZ00108 1043 lgyvrfkdIIKKKSEKITAEEEEGAEEDDEADDEDDEEELGAAvsydyLLSMPIWSLTKEKVEKLNAELEKKEKELEKLK 1122
|
490 500 510
....*....|....*....|....*....|....*.
gi 239938679 454 SILSND------KKLLKVITNSLKALKKKYADTRRS 483
Cdd:PTZ00108 1123 NTTPKDmwledlDKFEEALEEQEEVEEKEIAKEQRL 1158
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
23-455 |
5.99e-22 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 102.09 E-value: 5.99e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 23 YSKYIIqDRALPDARDGLKPVQRRILYAmhtdgnTFDKNFR---KAAKTVGNVI--GNYHpHGDSSVYEAMVRMSQDW-K 96
Cdd:PLN03128 666 FSQADL-ARSIPSMVDGLKPSQRKVLFA------CFKRNLKseiKVAQLSGYVAehSAYH-HGEASLASTIIGMAQDFvG 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 97 VRNV-LIEMHGNNGS--IDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVpNFDDTSKEPVVLPAMFPNLLVNGSTGI 173
Cdd:PLN03128 738 SNNInLLTPSGQFGTrlQGGKDAASARYIFTRLSPITRALFPKDDDVLLNYL-NEDGQSIEPEWYCPIIPMVLVNGSEGI 816
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 174 SAGYATDIPPHHLGEVIdAVIKRiqmpscsvdelmeVIKGPDFP---------TGGIIQGVDGIRKAYETgKGKIIIRGK 244
Cdd:PLN03128 817 GTGWSTFIPNYNPRDII-ANIRR-------------LLRGEELEpmhpwyrgfKGTITEVSTSRSGSYTV-TGIIEQIGD 881
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 245 AEIEtirggreqivITEIPFEV----NKANLVKKMDEFRIDKKVegISEVRDETDRTGLRVVIELKKE----ADAKGILN 316
Cdd:PLN03128 882 TTIR----------ITELPVRKwtqdYKEFLEALLTGTKKKEPE--IKDFKENHTDTTVHFTVTLSEEkmarALAEGLEK 949
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 317 FLYKNTDLQITynfNMVAIhNRRPMLM---SLPSILDAYIGH-------QKEVVTNRSVYELQKAKDRHHIVEGLMKA-- 384
Cdd:PLN03128 950 KFKLSTTISTS---NMHLF-DKDGKIKkydSPEDILEEFFHLrldlyvkRKEVLLENLEYELKKLDNKARFILAVVKGei 1025
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 385 ----------LSILDEVIATIRSSSDKRDAKNNLIAKYEFTEPQAEAI-----------VSLQLYRLTNTDITALKEEAE 443
Cdd:PLN03128 1026 vvnnrkraelLAELEEKGFDKFPKTAKISETNVVGDRDGEASEEEEASdnelaksydylLGMPISSLTLEKVDELRAERA 1105
|
490
....*....|..
gi 239938679 444 ELGKKIEELESI 455
Cdd:PLN03128 1106 KKETEVEELKKT 1117
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
31-209 |
4.84e-14 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 76.44 E-value: 4.84e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 31 RALPDARDGLKPVQRRILYAmhtdgnTFDKNFRKAAKT---VGNV--IGNYHpHGDSSVYEAMVRMSQDWKVRNV--LIE 103
Cdd:PLN03237 698 RSIPSMVDGLKPGQRKILFC------SFKRNFVKEAKVaqlSGYVseHSAYH-HGEQSLASTIIGMAQDFVGSNNinLLL 770
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938679 104 MHGNNG--SIDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVpNFDDTSKEPVVLPAMFPNLLVNGSTGISAGYATDI 181
Cdd:PLN03237 771 PNGQFGtrLQGGKDHASARYIFTRLSPITRFLFPKDDDILLDYL-NEDGQSIEPTWYMPIIPTVLVNGAEGIGTGWSTFI 849
|
170 180
....*....|....*....|....*...
gi 239938679 182 PPHHLGEVIDAVIKRIQmpscsvDELME 209
Cdd:PLN03237 850 PNYNPRDIVANIRRLLN------GESME 871
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
656-696 |
4.18e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 49.79 E-value: 4.18e-08
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 239938679 656 IFMATHLGYGLWFGEDEVNVVGARAAGVKGINLKEDDFVVS 696
Cdd:pfam03989 3 LLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVS 43
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
606-651 |
1.42e-07 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 48.64 E-value: 1.42e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 239938679 606 YLLFFTKNGMVKKTELTHYKAQ-RYSKALVALNLKGEDELIDVHVTN 651
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQgRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
704-752 |
1.33e-06 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 45.56 E-value: 1.33e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 239938679 704 DSIVLFTQRGAVKRMSLSEFEKTSRAKRGVVMLReLKKNpHRVVALFAC 752
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGIN-LKEG-DKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
549-599 |
8.34e-06 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 43.63 E-value: 8.34e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 239938679 549 DVLLLFTNKGSYIYCPVHQLPDIRWKDMGQHfsnLITIDRDETIVKAIPIK 599
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVK---GINLKEGDKVVSVLVVN 48
|
|
| |
