|
Name |
Accession |
Description |
Interval |
E-value |
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
3-860 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1590.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 3 MSTDEVRNAFLKFFESKGHQIVDSSSLVPHNDPTLLFTNAGMNQFKDCFLGAEKRAYTRATTAQRCVRAGGKHNDLENVG 82
Cdd:COG0013 2 MTSAEIRQKFLDFFESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKPPYPRATTSQKCVRTGGKHNDLENVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 83 FTARHHTFFEMLGNFSFGDYFKEDAIAFAWEFLTETLKLPKDRLLVTVYETDDEAFDIWNQKVGVPADRIIRIGdkkggk 162
Cdd:COG0013 82 YTARHHTFFEMLGNFSFGDYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDDDEAYDIWKKEIGVPEERIIRLG------ 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 163 qyESDNFWTMGDTGPCGPCTEIFYDHGEHIWGGRPGTPEEDGDRFIEIWNNVFMQFNRHADGTMEPLPKPSVDTGMGIER 242
Cdd:COG0013 156 --KKDNFWEMGDTGPCGPCSEIFYDRGPEYGGGPPGSPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDTGMGLER 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 243 ISAIMQGVHSNYEIDVFQKLIKATAEIVGC----EDLSNQSLRVIADHIRSCSFLIADGVMPSNEGRGYVLRRIIRRAVR 318
Cdd:COG0013 234 IAAVLQGVHSNYETDLFRPLIEAAAELTGVkygaDEEDDVSLRVIADHIRAVAFLIADGVLPSNEGRGYVLRRILRRAVR 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 319 HGNKLGAQGVFFHKLVGVLAEAMGSAADELKKQQAVVEKVLRIEEENFGRTLERGMVILNEALDALE---GKELDGETVF 395
Cdd:COG0013 314 HGRLLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAKLKaagGKVLSGEDAF 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 396 KLYDTYGFPADLTNDVAREREFTIDEAGFEKAMEEQRQRAREAGQFGTDYNAK------IKVDAQSEFCGYTSTQERSDV 469
Cdd:COG0013 394 KLYDTYGFPLDLTEEIARERGLTVDEEGFEAAMEEQRERARAAAKFSGDAAVDgvwrelLEEGGPTEFVGYDTLEAEAKV 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 470 VALFVEGEETATLSAGDKAIVILQETPFYAESGGQCGDSGVLKTESGLFQVEDTQK-LGNAIAHHGVLVEGVLAKGDQVT 548
Cdd:COG0013 474 LALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIEGDGGVFEVTDTQKpPGGLIVHIGKVEEGELKVGDTVT 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 549 AIVDAERRAAISLNHSATHLLHAALRQVLGEHVAQKGSLVKAENLRFDFSHLEAVTAAELKEVERLVNAQIRRNHAIETN 628
Cdd:COG0013 554 AQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAPDRLRFDFSHFEALTPEELAEIEDLVNEKIRENLPVETR 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 629 IMDIESAKQKGAMALFGEKYDDEVRVLSMGDFSTELCGGIHASNTGDIGLFKITSEGGIAAGIRRIEAVTGEAALEAIDA 708
Cdd:COG0013 634 EMPLDEAKALGAMALFGEKYGDEVRVVSIGDFSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALEYLRE 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 709 QARKFEE--------------KLQDAANKAKSLEKEIQQLKDKLASQASANLIDQVKEIAGVKVLVAKLDGADNKALRGM 774
Cdd:COG0013 714 QEALLKElaellkappeelpeRVEALLEELKELEKELEQLKAKLASAAADDLLAQAEEIGGVKVLAARVEGVDAKDLRDL 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 775 VDELKNQMGSGIIMLGNVADDKVGLIAGVTQDLTSK-VKAGELVNMVAQQVGGKGGGRPDMAQAGGTDSSALPSALASVD 853
Cdd:COG0013 794 ADDLKDKLGSGVVVLASVADGKVSLVAGVTKDLVKKgLKAGDLVKEVAKIVGGGGGGRPDMAQAGGKDPSKLDEALAAVK 873
|
....*..
gi 29611879 854 AWIAERL 860
Cdd:COG0013 874 EWLAEKL 880
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
7-839 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 1119.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 7 EVRNAFLKFFESKGHQIVDSSSLVPHNDPTLLFTNAGMNQFKDCFLGAEKRAYTRATTAQRCVRAggkhNDLENVGFTAR 86
Cdd:TIGR00344 1 EIRQTFLDFFKEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPSNRLTNAQPCIRL----NDLENVGRTAR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 87 HHTFFEMLGNFSFGDYFKEDAIAFAWEFLTETLKLPKDRLLVTVYETDDEAFDIWNqKVGVPADRIIRIGDKkggkqyes 166
Cdd:TIGR00344 77 HHTLFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLDKERLYVTVYEDDEEAYKIWE-KIGIPADRIIKCDAK-------- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 167 DNFWTMGDtGPCGPCTEIFYDHgehiWGGRPGTPEEDGDRFIEIWNNVFMQFNRHADGTMEPLPKPSVDTGMGIERISAI 246
Cdd:TIGR00344 148 DNFWDMGD-GPCGPCTEIYYDF----VGGKPGEPLEENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFVAV 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 247 MQGVHSNYEIDVFQKLIKATAEIVGCEDLSN-------------QSLRVIADHIRSCSFLIADGVMPSNEGRGYVLRRII 313
Cdd:TIGR00344 223 LQGVPTNYDTDIFLPLIEKIEEITGVKYDSNnagimdekrvedlRSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRRLI 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 314 RRAVRHGNKLGAQGVFFHKLVGVLAEAMGSAADELKKQQAVVEKVLRIEEENFGRTLERGMVILNEALDALEGKELDGET 393
Cdd:TIGR00344 303 RRALRHGKKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTGKKELDGED 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 394 VFKLYDTYGFPADLTNDVAREREFTIDEAGFEKAMEEQRQRAREAGQFGTDYNAKIKVDAQSEFCGYTSTQERSDVVALF 473
Cdd:TIGR00344 383 AFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQFQEQEIALVNVYPATEFLGYDDLEFEAKVIGLF 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 474 VEGEETATLSAGDKAIVILQETPFYAESGGQCGDSGVLKTESGLFQVEDTQKLGNAIAHHGVLVEGVLAKGDQVTAIVDA 553
Cdd:TIGR00344 463 DDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLIANDGKFRVVDVQKPNGVVFHFGEVEGGSLKVGDKVIAVIDE 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 554 ERRAAISLNHSATHLLHAALRQVLGEHVAQKGSLVKAENLRFDFSHLEAVTAAELKEVERLVNAQIRRNHAIETNIMDIE 633
Cdd:TIGR00344 543 KRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTREELEEIEDLANEQILANIPIKVIFMDLD 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 634 SAKQKGAMALFGEKY--DDEVRVLSMGDFSTELCGGIHASNTGDIGLFKITSEGGIAAGIRRIEAVTGEAALEAIDAQAR 711
Cdd:TIGR00344 623 EAKRKGAFALFGEKYvpGEKVRVVSVGDFSVELCGGTHVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEYLNEQED 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 712 KFEE----------KLQDAANK----AKSLEKEIQQLKDKLASQASANLIDQVKEIAGVKVLVAKLDGADNKALRGMVDE 777
Cdd:TIGR00344 703 KLKEladilkvtpnELPKKVERffeeWKALQKELESLKLKIADQKIDELKDKAETINGVKVLVEVVDAKDMKSLKTMADR 782
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 29611879 778 LKNQMGSGIIMLGNVADDKVGLIAGVTQDL-TSKVKAGELVNMVAQQVGGKGGGRPDMAQAGG 839
Cdd:TIGR00344 783 LKSKLGSAIYVLASFAEGKVKLVCGVSNDVlTKKIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
3-850 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 996.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 3 MSTDEVRNAFLKFFESKGHQIVDSSSLVPHNDPTLLFTNAGMNQFKDCFLG-----AEKRAYTRATTAQRCVRAGGKHND 77
Cdd:PLN02900 11 WPGDRIRRTFLSFFESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGtadpnTPLRKLPRATNTQKCIRAGGKHND 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 78 LENVGFTARHHTFFEMLGNFSFGDYFKEDAIAFAWEFLTETLKLPKDRLLVTVYETDD------EAFDIWNQKvgVPADR 151
Cdd:PLN02900 91 LDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEkqapddEARAIWLDY--LPEER 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 152 IIRIGDKkggkqyesDNFWTMGDTGPCGPCTEIFYD-HGEHiwgGRPGTPEEDGDRFIEIWNNVFMQFNRHADGTMEPLP 230
Cdd:PLN02900 169 VLPFGCK--------DNFWEMGDTGPCGPCSEIHYDrIGER---DAADLVNNDDPRFIEIWNLVFIQFNREADGSLKPLP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 231 KPSVDTGMGIERISAIMQGVHSNYEIDVFQKLIKATAEIVGCEDLSNQS-----------LRVIADHIRSCSFLIADGVM 299
Cdd:PLN02900 238 AKHVDTGMGLERLASILQNKPSNYDTDLFMPIFDAIQEATGARPYAGKVgaedddrvdmaYRVVADHIRTLSFAIADGVV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 300 PSNEGRGYVLRRIIRRAVRHGN-KLGAQGVFFHKLVGVLAEAMGSAADELKKQQAVVEKVLRIEEENFGRTLERGMVILN 378
Cdd:PLN02900 318 PSNEGRGYVLRRLLRRAVRYGRlLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFK 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 379 EALDAL---EGKELDGETVFKLYDTYGFPADLTNDVAREREFTIDEAGFEKAMEEQRQRAREAGQFG-----------TD 444
Cdd:PLN02900 398 KALAAAkanGGPVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRAAHLKAgggaielaaeaTS 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 445 YNAKIKVDAQSEFCGYTSTQE-RSDVVALFVEGEETATLSAGDKAIVILQETPFYAESGGQCGDSGVLKTESGL-FQVED 522
Cdd:PLN02900 478 WLQKQGVAATDDFLKYDWLSDhEAVVKAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLEGSGGAvVEVSD 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 523 TQKLGNAIAHHGVLVEGVLAKGDQVTAIVDAERRAAISLNHSATHLLHAALRQVLGEHVAQKGSLVKAENLRFDFSHLEA 602
Cdd:PLN02900 558 VQKAGGFVLHIGTVTEGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRFDFSHGKP 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 603 VTAAELKEVERLVNAQIRRNHAIETNIMDIESAKQ-KGAMALFGEKYDDEVRVLSMGD-FSTELCGGIHASNTGDIGLFK 680
Cdd:PLN02900 638 MTPEELREVESLVNEWIGDALPVEAKEMPLADAKRiNGLRAVFGEKYPDPVRVVSVGGvYSMELCGGTHVSNTAEAEAFK 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 681 ITSEGGIAAGIRRIEAVTGEAALEAIdAQARKFEEKLqDAANKAK---------------------------------SL 727
Cdd:PLN02900 718 LLSEEGIAKGIRRITAVTGGAAVEAI-NAADSLEREL-DSALKVEgsdlekkvaslksrvdaavipaakkeeirarvsAL 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 728 EKEIQQLKDKLASQASANLIDQVKEIA------GVKVLVAKLD-GADNKALRGMVDELKNQMGSGIIML--GNVADDKVG 798
Cdd:PLN02900 796 QKELRAAQKEAAALRAKLAVAKATELAskalsaGKSVLVARLDvGVDAAALKEAAEKVIAKLGDPAAVVlsSDEEKGKVS 875
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|...
gi 29611879 799 LIAGVTQDLTSK-VKAGELVNMVAQQVGGKGGGRPDMAQAGGTDSSALPSALA 850
Cdd:PLN02900 876 LVAAVPPGVVKKgLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEKLDAALE 928
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
7-555 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 795.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 7 EVRNAFLKFFESKGHQIVDSSSLVPHNDPTLLFTNAGMNQFKDCFLGAE-KRAYTRATTAQRCVRAGgkhnDLENVGFTA 85
Cdd:pfam01411 1 EIRQTFLDFFEKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVaKPPYNRATNSQKCIRAG----DLENVGRTG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 86 RHHTFFEMLGNFSFGDYFKEDAIAFAWEFLTETLKLPKDRLLVTVYETDDEAFDIWNQKVGVPADRIIRIGDKkggkqye 165
Cdd:pfam01411 77 RHHTFFEMLGNFSFGDYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDDEAGPIWEKIVGGPEERILRFGDK------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 166 sDNFWTMGDTGPCGPCTEIFYDHGEHIWGGRP-GTPEEDGDRFIEIWNNVFMQFNRHADGTMEPLPKPSVDTGMGIERIS 244
Cdd:pfam01411 150 -DNFWEMGDTGPCGPCSEIDYDRGEEIGGWDSgGTPTADDDRFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGLERLV 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 245 AIMQGVHSNYEIDVFQKLIKATAEIVG----CEDLSNQSLRVIADHIRSCSFLIADGVMPSNEGRGYVLRRIIRRAVRHG 320
Cdd:pfam01411 229 AVLQDVRSNYDTDVFIPVIELIEEISGaryyTVDETDEAYRVIADHTRALTFALADGVVPSNEGRGYVLRRILRRAVRHA 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 321 NKLGAQGVFFHKLVGVLAEAMGSAADELKKQQAVVEKVLRIEEENFGRTLERGMVILNEALDAL--EGKELDGETVFKLY 398
Cdd:pfam01411 309 KKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLkkGKKTLPGEDAFKLY 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 399 DTYGFPADLTNDVAREREFTIDEAGFEKAMEEQRQRAREAGQFG---TDYNAKIKVDAQSEFCGYTSTQERSDVVALFVE 475
Cdd:pfam01411 389 DTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEKgekLDVSALKELPATTEFLGYDDLESEAKILALPKD 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 476 GEETATLSAGDKAIVILQETPFYAESGGQCGDSGVLKTESGLFQVEDTQKLGNAIAHHGVLVEGVLAKGDQVTAIVDAER 555
Cdd:pfam01411 469 GEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYIIGDGGEFRVTDVQKYGGVVVHKGKLESGKLKVGDKVIAVIDEDR 548
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
5-250 |
1.39e-139 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 413.29 E-value: 1.39e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 5 TDEVRNAFLKFFESKGHQIVDSSSLVPHNDPTLLFTNAGMNQFKDCFLGAEKRAYTRATTAQRCVRAGGKHNdlenVGFT 84
Cdd:cd00673 1 ASEIRETFLSFFEKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPANRLVNSQKCIRAGDIDN----VGKT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 85 ARHHTFFEMLGNFSFGDYFKEDAIAFAWEFLTETLKLPKDRLLVTVYETDDEAFDIWNQKVGVPADRIIRIGDKkggkqy 164
Cdd:cd00673 77 GRHHTFFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGDDEEEAIWWWKIGLPGIRIERIGFK------ 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 165 esDNFWTMGDTGPCGPCTEIFYDHGEHIWGGRpgTPEEDGDRFIEIWNNVFMQFNRHADGTMEPLPKPSVDTGMGIERIS 244
Cdd:cd00673 151 --DNFWEMGGNGPCGPCSEIFYDRGEERDAAS--LPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLERLV 226
|
....*.
gi 29611879 245 AIMQGV 250
Cdd:cd00673 227 WVLQGV 232
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
652-694 |
3.55e-19 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 81.27 E-value: 3.55e-19
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 29611879 652 VRVLSMGDFSTELCGGIHASNTGDIGLFKITSEGGIAAGIRRI 694
Cdd:smart00863 1 VRVVSIGDFSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
3-860 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1590.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 3 MSTDEVRNAFLKFFESKGHQIVDSSSLVPHNDPTLLFTNAGMNQFKDCFLGAEKRAYTRATTAQRCVRAGGKHNDLENVG 82
Cdd:COG0013 2 MTSAEIRQKFLDFFESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKPPYPRATTSQKCVRTGGKHNDLENVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 83 FTARHHTFFEMLGNFSFGDYFKEDAIAFAWEFLTETLKLPKDRLLVTVYETDDEAFDIWNQKVGVPADRIIRIGdkkggk 162
Cdd:COG0013 82 YTARHHTFFEMLGNFSFGDYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDDDEAYDIWKKEIGVPEERIIRLG------ 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 163 qyESDNFWTMGDTGPCGPCTEIFYDHGEHIWGGRPGTPEEDGDRFIEIWNNVFMQFNRHADGTMEPLPKPSVDTGMGIER 242
Cdd:COG0013 156 --KKDNFWEMGDTGPCGPCSEIFYDRGPEYGGGPPGSPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDTGMGLER 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 243 ISAIMQGVHSNYEIDVFQKLIKATAEIVGC----EDLSNQSLRVIADHIRSCSFLIADGVMPSNEGRGYVLRRIIRRAVR 318
Cdd:COG0013 234 IAAVLQGVHSNYETDLFRPLIEAAAELTGVkygaDEEDDVSLRVIADHIRAVAFLIADGVLPSNEGRGYVLRRILRRAVR 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 319 HGNKLGAQGVFFHKLVGVLAEAMGSAADELKKQQAVVEKVLRIEEENFGRTLERGMVILNEALDALE---GKELDGETVF 395
Cdd:COG0013 314 HGRLLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAKLKaagGKVLSGEDAF 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 396 KLYDTYGFPADLTNDVAREREFTIDEAGFEKAMEEQRQRAREAGQFGTDYNAK------IKVDAQSEFCGYTSTQERSDV 469
Cdd:COG0013 394 KLYDTYGFPLDLTEEIARERGLTVDEEGFEAAMEEQRERARAAAKFSGDAAVDgvwrelLEEGGPTEFVGYDTLEAEAKV 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 470 VALFVEGEETATLSAGDKAIVILQETPFYAESGGQCGDSGVLKTESGLFQVEDTQK-LGNAIAHHGVLVEGVLAKGDQVT 548
Cdd:COG0013 474 LALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIEGDGGVFEVTDTQKpPGGLIVHIGKVEEGELKVGDTVT 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 549 AIVDAERRAAISLNHSATHLLHAALRQVLGEHVAQKGSLVKAENLRFDFSHLEAVTAAELKEVERLVNAQIRRNHAIETN 628
Cdd:COG0013 554 AQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAPDRLRFDFSHFEALTPEELAEIEDLVNEKIRENLPVETR 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 629 IMDIESAKQKGAMALFGEKYDDEVRVLSMGDFSTELCGGIHASNTGDIGLFKITSEGGIAAGIRRIEAVTGEAALEAIDA 708
Cdd:COG0013 634 EMPLDEAKALGAMALFGEKYGDEVRVVSIGDFSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALEYLRE 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 709 QARKFEE--------------KLQDAANKAKSLEKEIQQLKDKLASQASANLIDQVKEIAGVKVLVAKLDGADNKALRGM 774
Cdd:COG0013 714 QEALLKElaellkappeelpeRVEALLEELKELEKELEQLKAKLASAAADDLLAQAEEIGGVKVLAARVEGVDAKDLRDL 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 775 VDELKNQMGSGIIMLGNVADDKVGLIAGVTQDLTSK-VKAGELVNMVAQQVGGKGGGRPDMAQAGGTDSSALPSALASVD 853
Cdd:COG0013 794 ADDLKDKLGSGVVVLASVADGKVSLVAGVTKDLVKKgLKAGDLVKEVAKIVGGGGGGRPDMAQAGGKDPSKLDEALAAVK 873
|
....*..
gi 29611879 854 AWIAERL 860
Cdd:COG0013 874 EWLAEKL 880
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
7-839 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 1119.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 7 EVRNAFLKFFESKGHQIVDSSSLVPHNDPTLLFTNAGMNQFKDCFLGAEKRAYTRATTAQRCVRAggkhNDLENVGFTAR 86
Cdd:TIGR00344 1 EIRQTFLDFFKEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPSNRLTNAQPCIRL----NDLENVGRTAR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 87 HHTFFEMLGNFSFGDYFKEDAIAFAWEFLTETLKLPKDRLLVTVYETDDEAFDIWNqKVGVPADRIIRIGDKkggkqyes 166
Cdd:TIGR00344 77 HHTLFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLDKERLYVTVYEDDEEAYKIWE-KIGIPADRIIKCDAK-------- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 167 DNFWTMGDtGPCGPCTEIFYDHgehiWGGRPGTPEEDGDRFIEIWNNVFMQFNRHADGTMEPLPKPSVDTGMGIERISAI 246
Cdd:TIGR00344 148 DNFWDMGD-GPCGPCTEIYYDF----VGGKPGEPLEENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFVAV 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 247 MQGVHSNYEIDVFQKLIKATAEIVGCEDLSN-------------QSLRVIADHIRSCSFLIADGVMPSNEGRGYVLRRII 313
Cdd:TIGR00344 223 LQGVPTNYDTDIFLPLIEKIEEITGVKYDSNnagimdekrvedlRSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRRLI 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 314 RRAVRHGNKLGAQGVFFHKLVGVLAEAMGSAADELKKQQAVVEKVLRIEEENFGRTLERGMVILNEALDALEGKELDGET 393
Cdd:TIGR00344 303 RRALRHGKKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTGKKELDGED 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 394 VFKLYDTYGFPADLTNDVAREREFTIDEAGFEKAMEEQRQRAREAGQFGTDYNAKIKVDAQSEFCGYTSTQERSDVVALF 473
Cdd:TIGR00344 383 AFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQFQEQEIALVNVYPATEFLGYDDLEFEAKVIGLF 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 474 VEGEETATLSAGDKAIVILQETPFYAESGGQCGDSGVLKTESGLFQVEDTQKLGNAIAHHGVLVEGVLAKGDQVTAIVDA 553
Cdd:TIGR00344 463 DDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLIANDGKFRVVDVQKPNGVVFHFGEVEGGSLKVGDKVIAVIDE 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 554 ERRAAISLNHSATHLLHAALRQVLGEHVAQKGSLVKAENLRFDFSHLEAVTAAELKEVERLVNAQIRRNHAIETNIMDIE 633
Cdd:TIGR00344 543 KRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTREELEEIEDLANEQILANIPIKVIFMDLD 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 634 SAKQKGAMALFGEKY--DDEVRVLSMGDFSTELCGGIHASNTGDIGLFKITSEGGIAAGIRRIEAVTGEAALEAIDAQAR 711
Cdd:TIGR00344 623 EAKRKGAFALFGEKYvpGEKVRVVSVGDFSVELCGGTHVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEYLNEQED 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 712 KFEE----------KLQDAANK----AKSLEKEIQQLKDKLASQASANLIDQVKEIAGVKVLVAKLDGADNKALRGMVDE 777
Cdd:TIGR00344 703 KLKEladilkvtpnELPKKVERffeeWKALQKELESLKLKIADQKIDELKDKAETINGVKVLVEVVDAKDMKSLKTMADR 782
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 29611879 778 LKNQMGSGIIMLGNVADDKVGLIAGVTQDL-TSKVKAGELVNMVAQQVGGKGGGRPDMAQAGG 839
Cdd:TIGR00344 783 LKSKLGSAIYVLASFAEGKVKLVCGVSNDVlTKKIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
3-850 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 996.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 3 MSTDEVRNAFLKFFESKGHQIVDSSSLVPHNDPTLLFTNAGMNQFKDCFLG-----AEKRAYTRATTAQRCVRAGGKHND 77
Cdd:PLN02900 11 WPGDRIRRTFLSFFESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGtadpnTPLRKLPRATNTQKCIRAGGKHND 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 78 LENVGFTARHHTFFEMLGNFSFGDYFKEDAIAFAWEFLTETLKLPKDRLLVTVYETDD------EAFDIWNQKvgVPADR 151
Cdd:PLN02900 91 LDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEkqapddEARAIWLDY--LPEER 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 152 IIRIGDKkggkqyesDNFWTMGDTGPCGPCTEIFYD-HGEHiwgGRPGTPEEDGDRFIEIWNNVFMQFNRHADGTMEPLP 230
Cdd:PLN02900 169 VLPFGCK--------DNFWEMGDTGPCGPCSEIHYDrIGER---DAADLVNNDDPRFIEIWNLVFIQFNREADGSLKPLP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 231 KPSVDTGMGIERISAIMQGVHSNYEIDVFQKLIKATAEIVGCEDLSNQS-----------LRVIADHIRSCSFLIADGVM 299
Cdd:PLN02900 238 AKHVDTGMGLERLASILQNKPSNYDTDLFMPIFDAIQEATGARPYAGKVgaedddrvdmaYRVVADHIRTLSFAIADGVV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 300 PSNEGRGYVLRRIIRRAVRHGN-KLGAQGVFFHKLVGVLAEAMGSAADELKKQQAVVEKVLRIEEENFGRTLERGMVILN 378
Cdd:PLN02900 318 PSNEGRGYVLRRLLRRAVRYGRlLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFK 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 379 EALDAL---EGKELDGETVFKLYDTYGFPADLTNDVAREREFTIDEAGFEKAMEEQRQRAREAGQFG-----------TD 444
Cdd:PLN02900 398 KALAAAkanGGPVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRAAHLKAgggaielaaeaTS 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 445 YNAKIKVDAQSEFCGYTSTQE-RSDVVALFVEGEETATLSAGDKAIVILQETPFYAESGGQCGDSGVLKTESGL-FQVED 522
Cdd:PLN02900 478 WLQKQGVAATDDFLKYDWLSDhEAVVKAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLEGSGGAvVEVSD 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 523 TQKLGNAIAHHGVLVEGVLAKGDQVTAIVDAERRAAISLNHSATHLLHAALRQVLGEHVAQKGSLVKAENLRFDFSHLEA 602
Cdd:PLN02900 558 VQKAGGFVLHIGTVTEGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRFDFSHGKP 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 603 VTAAELKEVERLVNAQIRRNHAIETNIMDIESAKQ-KGAMALFGEKYDDEVRVLSMGD-FSTELCGGIHASNTGDIGLFK 680
Cdd:PLN02900 638 MTPEELREVESLVNEWIGDALPVEAKEMPLADAKRiNGLRAVFGEKYPDPVRVVSVGGvYSMELCGGTHVSNTAEAEAFK 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 681 ITSEGGIAAGIRRIEAVTGEAALEAIdAQARKFEEKLqDAANKAK---------------------------------SL 727
Cdd:PLN02900 718 LLSEEGIAKGIRRITAVTGGAAVEAI-NAADSLEREL-DSALKVEgsdlekkvaslksrvdaavipaakkeeirarvsAL 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 728 EKEIQQLKDKLASQASANLIDQVKEIA------GVKVLVAKLD-GADNKALRGMVDELKNQMGSGIIML--GNVADDKVG 798
Cdd:PLN02900 796 QKELRAAQKEAAALRAKLAVAKATELAskalsaGKSVLVARLDvGVDAAALKEAAEKVIAKLGDPAAVVlsSDEEKGKVS 875
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|...
gi 29611879 799 LIAGVTQDLTSK-VKAGELVNMVAQQVGGKGGGRPDMAQAGGTDSSALPSALA 850
Cdd:PLN02900 876 LVAAVPPGVVKKgLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEKLDAALE 928
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
7-555 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 795.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 7 EVRNAFLKFFESKGHQIVDSSSLVPHNDPTLLFTNAGMNQFKDCFLGAE-KRAYTRATTAQRCVRAGgkhnDLENVGFTA 85
Cdd:pfam01411 1 EIRQTFLDFFEKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVaKPPYNRATNSQKCIRAG----DLENVGRTG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 86 RHHTFFEMLGNFSFGDYFKEDAIAFAWEFLTETLKLPKDRLLVTVYETDDEAFDIWNQKVGVPADRIIRIGDKkggkqye 165
Cdd:pfam01411 77 RHHTFFEMLGNFSFGDYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDDEAGPIWEKIVGGPEERILRFGDK------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 166 sDNFWTMGDTGPCGPCTEIFYDHGEHIWGGRP-GTPEEDGDRFIEIWNNVFMQFNRHADGTMEPLPKPSVDTGMGIERIS 244
Cdd:pfam01411 150 -DNFWEMGDTGPCGPCSEIDYDRGEEIGGWDSgGTPTADDDRFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGLERLV 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 245 AIMQGVHSNYEIDVFQKLIKATAEIVG----CEDLSNQSLRVIADHIRSCSFLIADGVMPSNEGRGYVLRRIIRRAVRHG 320
Cdd:pfam01411 229 AVLQDVRSNYDTDVFIPVIELIEEISGaryyTVDETDEAYRVIADHTRALTFALADGVVPSNEGRGYVLRRILRRAVRHA 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 321 NKLGAQGVFFHKLVGVLAEAMGSAADELKKQQAVVEKVLRIEEENFGRTLERGMVILNEALDAL--EGKELDGETVFKLY 398
Cdd:pfam01411 309 KKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLkkGKKTLPGEDAFKLY 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 399 DTYGFPADLTNDVAREREFTIDEAGFEKAMEEQRQRAREAGQFG---TDYNAKIKVDAQSEFCGYTSTQERSDVVALFVE 475
Cdd:pfam01411 389 DTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEKgekLDVSALKELPATTEFLGYDDLESEAKILALPKD 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 476 GEETATLSAGDKAIVILQETPFYAESGGQCGDSGVLKTESGLFQVEDTQKLGNAIAHHGVLVEGVLAKGDQVTAIVDAER 555
Cdd:pfam01411 469 GEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYIIGDGGEFRVTDVQKYGGVVVHKGKLESGKLKVGDKVIAVIDEDR 548
|
|
| PRK01584 |
PRK01584 |
alanyl-tRNA synthetase; Provisional |
3-700 |
0e+00 |
|
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain] Cd Length: 594 Bit Score: 551.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 3 MSTDEVRNAFLKFFESKGHQIVDSSSLVPHNDPTLLFTNAGMNQFKDCFLGAEKRAYTRATTAQRCVRAGgkhnDLENVG 82
Cdd:PRK01584 1 MTLDELRKKYIDFFKSKGHVEIAGKSLIPENDPTVLFTTAGMHPLVPYLLGEPHPSGTRLVDVQKCLRTG----DIDEVG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 83 fTARHHTFFEMLGNFSFGDYFKEDAIAFAWEFLT--ETLKLPKDRLLVTVYETDD------EAFDIWnQKVGVPADRIIR 154
Cdd:PRK01584 77 -DLSHLTFFEMLGNWSLGAYFKEESIKYSFEFLTspDYLNIPKDKLYVTVFEGDEeiprdeETASVW-ESLGIPKDRIFY 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 155 IGdkkggkqyESDNFW-TMGDTGPCGPCTEIFYDHGEHIWGGRPGtPEEDGDRFIEIWNNVFMQFNRHADGTMEPLPKPS 233
Cdd:PRK01584 155 LS--------REHNWWgPVGETGPCGPDTEIFVDTGKPKCSVNCR-PTCSCGKYFEIWNNVFMQYNKDEDGNYEELKRKC 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 234 VDTGMGIERISAIMQGVHSNYEIDVFQKLIKATAEIV----GCEDLSNQSLRVIADHIRSCSFLIAD--GVMPSNEGRGY 307
Cdd:PRK01584 226 VDTGMGIERTIAFLQGKSSVYDTEAFTPIIKRIEKISgkiyGQNEEDDRSIRIIADHIRAACFILGDpfVVLPSNVGQGY 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 308 VLRRIIRRAVRHGNKLGAQGVFFHKLVGVLAEAMGSAADELKKQQAVVEKVLRIEEENFGRTLERGMVILNEALDAL-EG 386
Cdd:PRK01584 306 VLRRLIRRSIRHAKKLGIESHFLADLVDSVEEIYGSFYPELTEKKDFIKEELNKEEEKFFKTLRKGEQEFIKLIPNLgSS 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 387 KELDGETVFKLYDTYGFPADLTNDVAREREFTIDEAGFEKAMEEQRQRAREAGQfgtdynakikvdaqsefcgytstqer 466
Cdd:PRK01584 386 KIIPGDIAFKLYDTYGFPYEITEELASEYGFTVDREGFDEHFKKHQKVSKKGAD-------------------------- 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 467 sdvvalfvegeetatlsagdkaivilqetpfyaesggqcgdsgvlktesglfqvedtQKLGNAIAHHgvlvegvlakGDQ 546
Cdd:PRK01584 440 ---------------------------------------------------------KVFKGGLADH----------SYE 452
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 547 VTAIvdaerraaislnHSATHLLHAALRQVLGEHVAQKGSLVKAENLRFDFSHLEAVTAAELKEVERLVNAQIRRNHAIE 626
Cdd:PRK01584 453 TTKL------------HTATHLLHKALRLVLGDHVRQKGSNITAERLRFDFSHPEKMTDDEIKKVEDIVNLQIKNDLSVK 520
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 29611879 627 TNIMDIESAKQKGAMALFGEKYDDEVRVLSMGDFSTELCGGIHASNTGDIGLFKITSEGGIAAGIRRIEAVTGE 700
Cdd:PRK01584 521 KEVMSLEEAREKGAMALFGEKYEDIVKVYEIDGFSKEVCGGPHVENTGELGTFKIQKEQSSSSGVRRIRAILID 594
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
5-250 |
1.39e-139 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 413.29 E-value: 1.39e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 5 TDEVRNAFLKFFESKGHQIVDSSSLVPHNDPTLLFTNAGMNQFKDCFLGAEKRAYTRATTAQRCVRAGGKHNdlenVGFT 84
Cdd:cd00673 1 ASEIRETFLSFFEKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPANRLVNSQKCIRAGDIDN----VGKT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 85 ARHHTFFEMLGNFSFGDYFKEDAIAFAWEFLTETLKLPKDRLLVTVYETDDEAFDIWNQKVGVPADRIIRIGDKkggkqy 164
Cdd:cd00673 77 GRHHTFFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGDDEEEAIWWWKIGLPGIRIERIGFK------ 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 165 esDNFWTMGDTGPCGPCTEIFYDHGEHIWGGRpgTPEEDGDRFIEIWNNVFMQFNRHADGTMEPLPKPSVDTGMGIERIS 244
Cdd:cd00673 151 --DNFWEMGGNGPCGPCSEIFYDRGEERDAAS--LPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLERLV 226
|
....*.
gi 29611879 245 AIMQGV 250
Cdd:cd00673 227 WVLQGV 232
|
|
| AlaX |
COG2872 |
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis] ... |
479-700 |
2.95e-34 |
|
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442119 [Multi-domain] Cd Length: 238 Bit Score: 131.08 E-value: 2.95e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 479 TAT-LSAGDKAIVILQETPFYAESGGQCGDSGVLKTESGLFQVEDTQKLGNAIAHhgvLVEG--VLAKGDQVTAIVDAER 555
Cdd:COG2872 16 EATvTAVTEEGGVVLDRTAFYPTGGGQPGDTGTLVWDGKEIRVVDVRKEDGEIVH---VLEGapLPEVGDEVTGEIDWER 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 556 RAAISLNHSATHLLHAALRQVLGEHVAqkGSLVKAENLRFDFShLEAVTAAELKEVERLVNAQIRRNHAIETNIMDIESA 635
Cdd:COG2872 93 RYRHMRLHTALHLLSAVVYREYGAPVT--GGQIGEDRARIDFD-LPEFDEEDLEEIEAEANELIAADLPVRIYWITREEL 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 29611879 636 KQ-----KGAMALFGEKyDDEVRVLSMGDFSTELCGGIHASNTGDIGLFKIT---SEGgiaAGIRRIEAVTGE 700
Cdd:COG2872 170 EAipglvRTMSVLPPPG-VGRVRIVEIGGVDLQPCGGTHVANTGEIGRIKITkieKKG---KGNRRVYFTLGE 238
|
|
| DHHA1 |
pfam02272 |
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called ... |
722-856 |
3.86e-28 |
|
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA1 for DHH associated domain. This domain is diagnostic of DHH subfamily 1 members. This domains is also found in alanyl tRNA synthetase, suggesting that this domain may have an RNA binding function. The domain is about 60 residues long and contains a conserved GG motif.
Pssm-ID: 396724 [Multi-domain] Cd Length: 139 Bit Score: 110.22 E-value: 3.86e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 722 NKAKSLEKEIQQLKDKLASQASANLIDQVKEIAGVKVLVAKL-DGADNKALRGMVDELKNQMGSGIIML-GNVADDKVGL 799
Cdd:pfam02272 6 EELKELEKELEELKEALALLKAKELLEKAEEINGVKVLVAEVgEGWDAGALGIAADRLKKKLGDPVIVLvAKEDGDKVKV 85
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 29611879 800 IAGVTQDltSKVKAGELVNMVAQQVGGKGGGRpDMAQAGGTDSSALPSALASVDAWI 856
Cdd:pfam02272 86 SARSSKD--KGVDAGELLKEVAAILGGGGGGH-DLAAGAGIDAEKLDEALELLEEAI 139
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
652-694 |
3.55e-19 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 81.27 E-value: 3.55e-19
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 29611879 652 VRVLSMGDFSTELCGGIHASNTGDIGLFKITSEGGIAAGIRRI 694
Cdd:smart00863 1 VRVVSIGDFSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| tRNA_SAD |
pfam07973 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of ... |
652-694 |
3.65e-17 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 429764 [Multi-domain] Cd Length: 43 Bit Score: 75.56 E-value: 3.65e-17
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 29611879 652 VRVLSMGDFSTELCGGIHASNTGDIGLFKITSEGGIAAGIRRI 694
Cdd:pfam07973 1 VRVVSIGDFDVDLCGGTHVPNTGEIGAFKILKGESKNKGLRRI 43
|
|
| PLN02961 |
PLN02961 |
alanine-tRNA ligase |
490-682 |
3.58e-14 |
|
alanine-tRNA ligase
Pssm-ID: 178546 [Multi-domain] Cd Length: 223 Bit Score: 72.42 E-value: 3.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 490 VILQETPFYAESGGQCGDSGVLKTESG--LFQVEDTQKLGNAIAHHGVLVEG------VLAKGDQVTAIVDAERRAAISL 561
Cdd:PLN02961 5 LVLDRTIFHPQGGGQPSDTGRIVISGGdtKFSVQDVRRKDGVVYHYGVFEGSnpesasPFEAGDEVTVTVDESRRKLHSR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 562 NHSATHLLHAALRQVlgehvaQKGSLVKAENLRF-DFSHLE---AVTAAEL----KEVERLVNAQIRRNHAIETNIMDIE 633
Cdd:PLN02961 85 LHSAGHLLDVCMARV------GLGPLEPGKGYHFpDGPFVEykgKIPQGELdskqDELEAEANELIAEGGKVSAAVLPYD 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 29611879 634 SAKQ--KGAMALFGEKyDDEVRVLSMGDFSTELCGGIHASNTGDIGLFKIT 682
Cdd:PLN02961 159 EAAElcGGSLPDYIAK-DSTPRIVKIGDSPGCPCGGTHVADVSEITSVKVT 208
|
|
| class_II_aaRS-like_core |
cd00768 |
Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA ... |
6-243 |
1.74e-07 |
|
Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. These enzymes are usually homodimers. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. The substrate specificity of this reaction is further determined by additional domains. Intererestingly, this domain is also found is asparagine synthase A (AsnA), in the accessory subunit of mitochondrial polymerase gamma and in the bacterial ATP phosphoribosyltransferase regulatory subunit HisZ.
Pssm-ID: 238391 [Multi-domain] Cd Length: 211 Bit Score: 52.51 E-value: 1.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 6 DEVRNAFLKFFESKGHQIVDSSSLvphnDPTLLFTNAG-----MNQFKDcflGAEKRAYTRATTAQRCVRAGGKH-NDL- 78
Cdd:cd00768 3 SKIEQKLRRFMAELGFQEVETPIV----EREPLLEKAGhepkdLLPVGA---ENEEDLYLRPTLEPGLVRLFVSHiRKLp 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 79 ------------ENVGFTARHHTFFEMLGNFSFGDYFKEDAIafawefltetlklpkDRLLVTVYEtddeafDIWnQKVG 146
Cdd:cd00768 76 lrlaeigpafrnEGGRRGLRRVREFTQLEGEVFGEDGEEASE---------------FEELIELTE------ELL-RALG 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 147 VPADRIIRIGDkkggkqyeSDNFWTmgdtGPCGPCTEIFYDHGEHiwggrpgtpeedgdRFIEIWNNVFM---QFNRHAD 223
Cdd:cd00768 134 IKLDIVFVEKT--------PGEFSP----GGAGPGFEIEVDHPEG--------------RGLEIGSGGYRqdeQARAADL 187
|
250 260
....*....|....*....|....
gi 29611879 224 GTMEPLPK----PSVDTGMGIERI 243
Cdd:cd00768 188 YFLDEALEyrypPTIGFGLGLERL 211
|
|
| ThrS |
COG0441 |
Threonyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Threonyl-tRNA ... |
540-683 |
2.49e-05 |
|
Threonyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Threonyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440210 [Multi-domain] Cd Length: 639 Bit Score: 48.10 E-value: 2.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 540 VLAKGDQVtAIVDAERRAAIS-LNHSATHLLHAALRQVLGE-HVAQkGSLVkaEN-LRFDFSHLEAVTAAELKEVERLVN 616
Cdd:COG0441 50 PIEEDAEL-EIVTFDDEEGLEiLRHSAAHLLAQAVKRLYPDaKLTI-GPVI--ENgFYYDFDLERPFTPEDLEKIEKEMK 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 617 AQIRRNHAIETNIMDIESAKqkgamALF---GEKY----------DDEVRVLSMGDFsTELCGGIHASNTGDIGLFKITS 683
Cdd:COG0441 126 EIIKEDLPIEREEVSREEAI-----ELFkekGEPYkveliedipeDEEISLYRQGEF-VDLCRGPHVPSTGKIKAFKLLS 199
|
|
| PRK12444 |
PRK12444 |
threonyl-tRNA synthetase; Reviewed |
561-686 |
7.64e-03 |
|
threonyl-tRNA synthetase; Reviewed
Pssm-ID: 183530 [Multi-domain] Cd Length: 639 Bit Score: 39.73 E-value: 7.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29611879 561 LNHSATHLLHAALRQVLGEHVAQKGSLVKaENLRFDFSHLEAVTAAELKEVERLVNAQIRRNHAIETNIMDIESAKqkga 640
Cdd:PRK12444 75 ARHSAAHILAQAVKRLYGDVNLGVGPVIE-NGFYYDMDLPSSVNVEDLRKIEKEMKKIINENIKIERVEVSREEAA---- 149
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 29611879 641 mALFGEKYD-------------DEVRVLSMGDFsTELCGGIHASNTGDIGLFKITSEGG 686
Cdd:PRK12444 150 -KLFQEMNDrlklelleaipsgESITLYKQGEF-VDLCRGPHLPSTGYLKAFQLTHVSG 206
|
|
| |
