The IBIS service is no longer available.
To investigate the conservation of protein-protein, protein-nucleic acid, and protein-ligand interactions please use the MMDB database
and pre-computed structural similarity as provided by VAST and VASTplus, which reports similarities of protein quaternary structures.
Shoemaker BA, Zhang D, Tyagi M, Thangudu RR, Fong JH, Marchler-Bauer A, Bryant SH, Madej T, Panchenko AR. (2012), IBIS (Inferred Biomolecular Interaction Server) reports, predicts and integrates multiple types of conserved interactions for proteins. Nucleic Acids Res. 40(Database issue): D834-40.